Sitalong DM 10mg/1000mg/100mg Tablet ER

Introduction

Sitalong DM is a prescription medication that combines three active ingredients: Dapagliflozin, Metformin, and Sitagliptin. It is available in tablet form and is used for the management of type 2 diabetes mellitus. This medication helps to control blood sugar levels by reducing glucose production in the liver, increasing glucose excretion through the kidneys, and enhancing the release of insulin from the pancreas.

Uses

Sitalong DM is prescribed for the treatment of type 2 diabetes mellitus. It is used to help lower blood sugar levels in individuals who are not able to adequately control their diabetes through diet and exercise alone. This medication is typically used in combination with a healthy diet and regular exercise to achieve optimal blood sugar control.

Dosage and Administration

The dosage of Sitalong DM will vary depending on individual patient factors such as age, renal function, and response to treatment. Follow the instructions provided by your healthcare provider. Typically, the recommended starting dose is one tablet taken orally once daily with a meal. Your doctor may adjust the dosage as needed to achieve the desired blood sugar control. Take this medication exactly as prescribed and not to exceed the recommended dose.

Mechanism of Action

Sitalong DM works through the combined action of its three active ingredients – Dapagliflozin, Metformin, and Sitagliptin. Dapagliflozin works by inhibiting the sodium-glucose cotransporter 2 (SGLT2) in the kidneys, which reduces the reabsorption of glucose and increases its excretion through urine. Metformin helps to reduce glucose production in the liver and improves insulin sensitivity in the body. Sitagliptin enhances the release of insulin from the pancreas and reduces the production of glucagon, a hormone that raises blood sugar levels. Together, these actions help to lower blood sugar levels and improve glycemic control in individuals with type 2 diabetes mellitus.

Side Effects

Common side effects may include:

• Nausea
• Vomiting
• Diarrhea
• Stomach upset
• Headache
• Urinary tract infections

If any of these side effects persist or worsen, contact your healthcare provider for further guidance. In rare cases, this medication may also cause serious side effects such as lactic acidosis (a buildup of lactic acid in the body) or allergic reactions. If you experience symptoms such as severe stomach pain, difficulty breathing, or rash, seek immediate medical attention.

Drug Interactions

Sitalong DM may interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. Inform your healthcare provider about all the medications and supplements you are currently taking to avoid potential drug interactions. Some common drug interactions to be aware of include:

• Insulin or insulin secretagogues: Increased risk of hypoglycemia (low blood sugar)
• Diuretics: Increased risk of dehydration and electrolyte imbalances
• CYP3A4 inhibitors or inducers: Potential changes in the blood levels of Sitalong DM
• Certain medications used to treat high blood pressure or heart failure: Increased risk of low blood pressure

Always consult with your healthcare provider or pharmacist for a comprehensive list of potential drug interactions and to ensure the safe and effective use of this medication.

Precautions

Before taking Sitalong DM, inform your healthcare provider about any existing medical conditions, including kidney problems, liver disease, heart disease, or a history of pancreatitis. This medication may not be suitable for individuals with certain medical conditions or those who are allergic to any of its ingredients. Avoid alcohol consumption while taking this medication, as it may increase the risk of lactic acidosis.

Storage

Sitalong DM should be stored at room temperature, away from moisture and heat. Keep this medication out of the reach of children and pets. Do not use this medication if the packaging is damaged or if the tablets appear discolored or have an unusual odor.

Patient Tips

• Take Sitalong DM exactly as prescribed by your healthcare provider. Do not skip doses or exceed the recommended dosage.
• This medication is typically taken with food to help reduce the risk of stomach upset.
• Regular monitoring of blood sugar levels is important to ensure optimal control of diabetes. Follow your healthcare provider’s instructions for blood sugar monitoring.
• Maintain a healthy diet and engage in regular physical activity as recommended by your healthcare provider.
• If you experience any unusual or persistent symptoms while taking this medication, contact your healthcare provider for further evaluation.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• About dapagliflozin (NHS UK) [Accessed 1 Jun. 2024] (online) Available at:
• Forxiga 10 mg film-coated tablets (Health Professionals SmPC) Available at:
• Dapagliflozin (Drugs.com) [Accessed 24 Jun. 2024] (online) Available at:
• dapagliflozin propaned 10 mg-metformin er 1,000 mg tablet,ext rel 24hr antihyperglycemic-sod/gluc cotransport-2 (sglt2) inhibitors (RX) [Accessed 23 Jun. 2024] (online) Available at:
• Dapagliflozin (MedlinePlus) [Accessed 25 Jun. 2024] (online) Available at:
• Dhillon S. Dapagliflozin: A Review in Type 2 Diabetes. Drugs. 2019 Jul;79(10):1135-1146. doi: 10.1007/s40265-019-01148-3. [Accessed 15 Jun. 2024] Available at: