Mannitol IV 20% Injection

Introduction

Mannitol IV is a medication that contains Mannitol as its active ingredient. It is available in the form of an injectable solution and is commonly prescribed by healthcare professionals.

Uses

Mannitol IV is primarily used for the treatment of increased intracranial pressure (ICP) and cerebral edema. It is often administered in emergency situations, such as traumatic brain injury, stroke, or brain surgery, where there is a risk of brain swelling.

Dosage and Administration

The dosage of Mannitol IV may vary depending on the patient’s condition and the healthcare professional’s recommendation. It is typically administered intravenously, under the supervision of a healthcare provider. The exact dose and frequency will be determined by your doctor. Follow their instructions carefully.

Mechanism of Action

Mannitol IV works by drawing water out of the brain cells, thereby reducing swelling and decreasing intracranial pressure. This helps to improve blood flow and oxygen supply to the brain, which is crucial for the recovery of patients with conditions such as cerebral edema.

Side Effects

Common side effects may include headache, nausea, vomiting, and increased urination. These side effects are usually mild and temporary. However, if they persist or worsen, consult your healthcare provider.

Serious side effects are rare but may include severe allergic reactions, such as difficulty breathing, rash, or swelling of the face, lips, tongue, or throat. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

inform your healthcare provider about all medications, supplements, and herbal products you are currently taking before starting Mannitol IV. Certain medications, such as diuretics and blood pressure medications, may interact with Mannitol, potentially increasing the risk of side effects or affecting its effectiveness. Your doctor will consider these potential interactions when determining the appropriate treatment plan for you.

Precautions

Before using Mannitol IV, discuss any pre-existing medical conditions or allergies with your healthcare provider. Inform them if you have a history of kidney problems or if you are allergic to Mannitol or any other ingredients in the medication.

Mannitol IV is contraindicated in patients with severe kidney impairment or heart failure. It should not be used in patients with known hypersensitivity to Mannitol.

Storage

Patient Tips

• Follow the dosage instructions provided by your healthcare provider.
• If you have any questions or concerns about the medication, don’t hesitate to ask your healthcare provider.
• Keep all scheduled appointments with your doctor to monitor your progress and response to the treatment.
• If you experience any unexpected or severe side effects, contact your healthcare provider immediately.
• Store the medication as directed and check the expiration date before using it.
• Do not use Mannitol IV if the solution appears discolored or contains particles.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Bortezomib 1mg powder for solution for injection (Health Professionals SmPC) Available at:
• Mannitol injection (Drugs.com) [Accessed 16 Jun. 2024] (online) Available at:
• mannitol 40 mg inhalation powder in a capsule (RX) [Accessed 22 Jun. 2024] (online) Available at:
• Drug Development Pipeline (Cystic Fibrosis Foundation) [Accessed 6 Jun. 2024] (online) Available at:
• Chen M, Zhang W, Wu H, Guang C, Mu W. Mannitol: physiological functionalities, determination methods, biotechnological production, and applications. Appl Microbiol Biotechnol. 2020 Aug;104(16):6941-6951. doi: 10.1007/s00253-020-10757-y. Epub 2020 Jun 29. [Accessed 19 Jun. 2024] Available at: