Oflodex TZ Tablet

Introduction

Oflodex TZ is a prescription medication that contains two active ingredients: Ofloxacin and Tinidazole. It is available under the brand name Oflodex TZ. This combination medication is commonly used to treat various bacterial and parasitic infections.

Uses

Oflodex TZ is primarily prescribed for the treatment of the following conditions:

• Bacterial infections: It can be used to treat infections caused by certain bacteria, such as urinary tract infections, respiratory tract infections, and skin and soft tissue infections.
• Parasitic infections: It is also effective in treating certain parasitic infections, including amoebiasis and giardiasis.

Dosage and Administration

The dosage of Oflodex TZ may vary depending on the specific infection being treated and the patient’s age, weight, and overall health. Follow the instructions provided by your healthcare professional or the directions on the prescription label.

Generally, Oflodex TZ is taken orally with a full glass of water. It can be taken with or without food, but it is recommended to take it with food to reduce the risk of stomach upset. The tablets should be swallowed whole and not crushed or chewed.

Complete the full course of medication as prescribed, even if the symptoms improve before the course is completed. Stopping the medication prematurely may result in the infection not being fully treated.

Mechanism of Action

Oflodex TZ contains two active ingredients that work together to combat infections:

• Ofloxacin belongs to a class of antibiotics known as fluoroquinolones. It works by inhibiting the enzymes necessary for the growth and reproduction of bacteria, thereby stopping the infection from spreading.
• Tinidazole is an antiprotozoal agent that works by interfering with the DNA synthesis of the parasites, leading to their death.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, headache, dizziness, and abdominal pain. These side effects are usually mild and temporary.

In some cases, more serious side effects may occur, although they are rare. These may include allergic reactions, severe skin reactions, signs of liver problems (such as yellowing of the skin or eyes, dark urine, or abdominal pain), and signs of nerve damage (such as tingling or numbness in the limbs). If you experience any of these serious side effects, seek medical attention immediately.

Drug Interactions

Oflodex TZ may interact with certain other medications, which can affect its effectiveness or increase the risk of side effects. Inform your healthcare professional about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements.

Some common drug interactions may occur with medicines that affect the liver enzymes, such as warfarin, theophylline, and phenytoin. Additionally, Oflodex TZ may enhance the effects of alcohol, leading to an increased risk of side effects such as dizziness and nausea.

Precautions

Before taking Oflodex TZ, inform your healthcare professional about any medical conditions you have, especially if you have a history of liver disease, kidney disease, or blood disorders. This medication should be used with caution in pregnant women, breastfeeding women, and children.

Oflodex TZ may interact with certain medications or substances, such as antacids, iron supplements, and caffeine. Follow your healthcare professional’s advice regarding these potential interactions.

Storage

Patient Tips

• Take Oflodex TZ exactly as prescribed by your healthcare professional.
• If you miss a dose, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not take a double dose to make up for a missed dose.
• While taking Oflodex TZ, stay well-hydrated by drinking plenty of fluids.
• If you experience any persistent or bothersome side effects, contact your healthcare professional for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• EXOCIN® 3 mg/ml Eye Drops, Solution. (Health Professionals SmPC) Available at:
• Ofloxacin (Drugs.com) [Accessed 24 Jun. 2024] (online) Available at:
• ofloxacin (RX) [Accessed 17 Jun. 2024] (online) Available at:
• Ofloxacin (MedlinePlus) [Accessed 25 Jun. 2024] (online) Available at:
• Hsiao SH, Chang CM, Tsao CJ, Lee YY, Hsu MY, Wu TJ. Acute rhabdomyolysis associated with ofloxacin/levofloxacin therapy. Ann Pharmacother. 2005 Jan;39(1):146-9. doi: 10.1345/aph.1E285. Epub 2004 Nov 23. [Accessed 13 Jun. 2024] Available at: