PATH G 15MG/1MG CAPSULE

Introduction

PATH G is a prescription medication that combines two active ingredients: Pioglitazone and Glimepiride. It is commonly prescribed to help manage blood sugar levels in patients with type 2 diabetes.

Uses

PATH G is primarily used to treat type 2 diabetes mellitus. It helps control blood sugar levels by improving insulin sensitivity and reducing the amount of glucose produced by the liver. This medication is typically prescribed alongside diet and exercise to achieve optimal glycemic control.

Dosage and Administration

The dosage of PATH G may vary depending on individual patient factors and the severity of their diabetes. Follow the specific instructions provided by your healthcare provider. Generally, the recommended starting dose for adults is one capsule taken orally once daily, with or without food. Your doctor may adjust the dose as needed to achieve the desired blood sugar control.

Mechanism of Action

Pioglitazone, one of the active ingredients in PATH G, belongs to a class of medications called thiazolidinediones. It works by increasing the body’s sensitivity to insulin, a hormone that helps regulate blood sugar levels. This allows insulin to work more effectively in lowering blood glucose levels. Glimepiride, on the other hand, is a sulfonylurea medication that stimulates the release of insulin from the pancreas, thereby reducing blood sugar levels.

Side Effects

Common side effects may include:

• Hypoglycemia: This is a condition characterized by low blood sugar levels. Symptoms may include dizziness, headache, shakiness, sweating, and confusion. If you experience these symptoms, promptly consume a source of fast-acting sugar, such as fruit juice or glucose tablets, and seek medical attention if necessary.
• Weight gain: Some patients may experience weight gain while taking PATH G. Monitor your weight regularly and discuss any concerns with your healthcare provider.
• Fluid retention: In rare cases, PATH G may cause fluid retention, leading to swelling in the legs or ankles. If you notice any unusual swelling, contact your doctor.

Serious side effects are rare but may include liver problems, heart failure, or an allergic reaction. If you experience any severe or persistent side effects, seek immediate medical attention.

Drug Interactions

PATH G may interact with other medications, including:

• Insulin or other oral antidiabetic medications: Combining PATH G with other medications that lower blood sugar levels may increase the risk of hypoglycemia. Your healthcare provider will carefully monitor your blood sugar levels and adjust your medications as needed.
• Certain medications affecting liver enzymes: Some medications may affect the way PATH G is metabolized in the body, potentially leading to increased or decreased drug levels. Inform your doctor about all the medications you are taking, including over-the-counter drugs and herbal supplements.

Consult your healthcare provider or pharmacist about potential drug interactions before starting PATH G.

Precautions

Before taking PATH G, inform your healthcare provider about any existing medical conditions, including liver or heart problems. Additionally, let your doctor know about any allergies or sensitivities you may have.

PATH G is not recommended for use in patients with severe heart failure or a history of bladder cancer. Discuss the potential risks and benefits of this medication with your healthcare provider.

Storage

PATH G should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of the reach of children and pets. Do not use PATH G if it has expired or if the packaging is damaged.

Patient Tips

• Take the medication as prescribed by your healthcare provider. Do not change the dose or stop taking the medication without consulting your doctor.
• Follow a healthy diet and exercise regularly to complement the effects of the medication.
• Monitor your blood sugar levels regularly and keep a record of the results. This will help you and your doctor assess the effectiveness of the treatment.
• Keep a source of fast-acting sugar, such as fruit juice or glucose tablets, with you at all times in case of hypoglycemia.
• Attend regular check-ups with your healthcare provider to monitor your progress and discuss any concerns or questions you may have.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Glimepiride: medicine to treat type 2 diabetes (NHS UK) [Accessed 4 Jun. 2024] (online) Available at:
• Glimepiride 1 mg tablets (Health Professionals SmPC) Available at:
• Glimepiride (Drugs.com) [Accessed 6 Jun. 2024] (online) Available at:
• glimepiride (amaryl) (RX) [Accessed 9 Jun. 2024] (online) Available at:
• Glimepiride (MedlinePlus) [Accessed 25 Jun. 2024] (online) Available at:
• Ridderstråle M, Andersen KR, Zeller C, Kim G, Woerle HJ, Broedl UC; EMPA-REG H2H-SU trial investigators. Comparison of empagliflozin and glimepiride as add-on to metformin in patients with type 2 diabetes: a 104-week randomised, active-controlled, double-blind, phase 3 trial. Lancet Diabetes Endocrinol. 2014 Sep;2(9):691-700. doi: 10.1016/S2213-8587(14)70120-2. Epub 2014 Jun 16. [Accessed 3 Jun. 2024] Available at: