Historil Syrup

Introduction

Historil is a medication that combines the active ingredients Terbutaline, Ambroxol, Guaifenesin, and a flavored mentholated base. It is available in syrup form and is commonly prescribed to patients for various respiratory conditions.

Uses

Historil is primarily used to relieve symptoms associated with respiratory conditions such as cough, chest congestion, and difficulty in breathing. It helps to thin and loosen mucus in the airways, making it easier to cough up and clear the lungs.

Dosage and Administration

The dosage of Historil may vary depending on the patient’s age, weight, and the severity of the condition. Follow the instructions provided by your healthcare professional or the directions on the product label.

Generally, the recommended dosage for adults and children over 12 years of age is 10 ml of syrup, three times a day. Children aged 6 to 12 years may take 5 ml of syrup, three times a day. For children under 6 years of age, the dosage should be determined by a healthcare professional.

Historil should be taken orally with or without food. Use the measuring device provided with the product to ensure accurate dosage.

Mechanism of Action

The active ingredients in Historil work in different ways to provide relief for respiratory symptoms:

• Terbutaline: It is a bronchodilator that helps to relax and open up the airways, making it easier to breathe.
• Ambroxol: It is an expectorant that helps to thin and loosen mucus in the respiratory tract, making it easier to cough up.
• Guaifenesin: It is also an expectorant that helps to increase the production of fluid in the respiratory tract, which helps to thin and loosen mucus.
• Flavored Mentholated Base: It provides a pleasant taste and may have a soothing effect on the throat.

Side Effects

Common side effects may include:

• Nausea
• Vomiting
• Upset stomach
• Diarrhea
• Headache
• Dizziness

These side effects are usually mild and go away on their own. However, if they persist or become bothersome, consult a healthcare professional.

In rare cases, some individuals may experience more serious side effects such as:

• Allergic reactions (rash, itching, swelling, difficulty breathing)
• Chest pain
• Irregular heartbeat
• Severe dizziness

If any of these serious side effects occur, seek immediate medical attention.

Drug Interactions

Historil may interact with certain medications, including:

• Beta-blockers
• Monoamine oxidase inhibitors (MAOIs)
• Other medications that contain terbutaline, ambroxol, or guaifenesin

inform your healthcare professional about all the medications you are taking, including prescription, over-the-counter, and herbal products, before starting Historil. They can assess the potential interactions and adjust your treatment plan accordingly.

Precautions

Before taking Historil, consider the following precautions:

• Inform your healthcare professional if you have any known allergies or sensitivities to any of the active ingredients or other medications.
• Discuss any existing medical conditions, especially heart or lung problems, diabetes, or high blood pressure, as they may affect the suitability of this medication.
• If you are pregnant or breastfeeding, consult your healthcare professional before using Historil, as the safety of this medication during pregnancy and breastfeeding has not been established.

Additionally, Historil may cause drowsiness or dizziness. Avoid activities that require alertness, such as driving or operating machinery, until you know how the medication affects you.

Storage

Historil should be stored in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets. Do not use the medication if it has passed the expiration date printed on the packaging.

Patient Tips

• Follow the dosage instructions provided by your healthcare professional or the product label.
• Use the measuring device provided with the product to ensure accurate dosage.
• If you miss a dose, take it as soon as you remember. If it is close to the next scheduled dose, skip the missed dose and resume your regular dosing schedule.
• Do not exceed the recommended dosage without consulting your healthcare professional.
• Drink plenty of fluids to help thin and loosen mucus.
• If your symptoms worsen or do not improve after a few days of treatment, consult your healthcare professional.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Chair-based pilates video workout (NHS UK) [Accessed 25 Jun. 2024] (online) Available at:
• Beechams All-in-One Oral solution (Health Professionals SmPC) Available at:
• Ambroxol (Drugs.com) [Accessed 30 Jun. 2024] (online) Available at:
• guaifenesin (OTC) [Accessed 25 Jun. 2024] (online) Available at:
• Guaifenesin (MedlinePlus) [Accessed 9 Jun. 2024] (online) Available at:
• Malerba M, Ragnoli B. Ambroxol in the 21st century: pharmacological and clinical update. Expert Opin Drug Metab Toxicol. 2008 Aug;4(8):1119-29. doi: 10.1517/17425255.4.8.1119. [Accessed 27 Jun. 2024] Available at: