Tonact Plus Tablet ER

Introduction

Tonact Plus ER is a prescription medication that combines two active ingredients: Atorvastatin and Vitamin B3. Atorvastatin is a type of medication known as a statin, which helps lower cholesterol levels in the blood. Vitamin B3, also known as niacin, is a water-soluble vitamin that plays a crucial role in maintaining overall health.

Uses

Tonact Plus ER is primarily prescribed to manage high cholesterol levels in individuals who are at risk of cardiovascular diseases such as heart attack or stroke. It is used as an adjunct to a healthy diet and exercise to lower cholesterol levels and reduce the risk of cardiovascular events.

Dosage and Administration

The dosage of Tonact Plus ER may vary depending on individual factors such as the severity of the condition and the patient’s response to treatment. Follow the instructions provided by your healthcare professional. Generally, the recommended starting dose is one tablet taken orally once daily, preferably with food. Your doctor may adjust the dosage based on your cholesterol levels and other medical factors.

Mechanism of Action

Atorvastatin, one of the active ingredients in Tonact Plus ER, works by inhibiting an enzyme in the liver called HMG-CoA reductase. This enzyme plays a key role in the production of cholesterol in the body. By inhibiting this enzyme, Atorvastatin helps reduce the levels of “bad” cholesterol (LDL) and triglycerides in the blood, while increasing the levels of “good” cholesterol (HDL). Vitamin B3, on the other hand, helps support overall cardiovascular health.

Side Effects

Common side effects may include headache, muscle aches, stomach pain, nausea, and diarrhea. These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, such as muscle weakness or liver problems, seek medical attention immediately.

Drug Interactions

Tonact Plus ER may interact with certain medications, including but not limited to:

• Other cholesterol-lowering medications
• Anticoagulant medications (blood thinners)
• Certain antibiotics, antifungals, and antiviral medications
• Grapefruit juice

inform your healthcare professional about all the medications you are currently taking, including over-the-counter drugs and supplements, to avoid potential drug interactions.

Precautions

Before taking Tonact Plus ER, inform your healthcare professional about any medical conditions you have, especially liver disease, kidney disease, or diabetes. Additionally, let your doctor know if you are pregnant, planning to become pregnant, or breastfeeding, as the safety of this medication during pregnancy and lactation has not been established.

Tonact Plus ER should not be taken if you are allergic to any of its ingredients. Avoid alcohol while taking this medication, as it may increase the risk of liver problems.

Storage

Tonact Plus ER should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Take Tonact Plus ER exactly as prescribed by your healthcare professional. Do not exceed the recommended dosage or stop taking the medication without consulting your doctor.
• Follow a healthy diet and exercise regularly while taking this medication to maximize its effectiveness.
• Attend regular check-ups with your doctor to monitor your cholesterol levels and overall health.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• If you have any questions or concerns about Tonact Plus ER, do not hesitate to consult your healthcare professional for further guidance and information.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Atorvastatin: a medicine to treat high blood cholestesterol (NHS UK) [Accessed 5 Jun. 2024] (online) Available at:
• Atorvastatin 10 mg film-coated tablets (Health Professionals SmPC) Available at:
• Atorvastatin (Drugs.com) [Accessed 4 Jun. 2024] (online) Available at:
• atorvastatin (RX) [Accessed 21 Jun. 2024] (online) Available at:
• Atorvastatin (MedlinePlus) [Accessed 1 Jun. 2024] (online) Available at:
• Yu L, Liu S, Zhou R, Sun H, Su X, Liu Q, Li S, Ying J, Zhao F, Mu D, Qu Y. Atorvastatin inhibits neuronal apoptosis via activating cAMP/PKA/p-CREB/BDNF pathway in hypoxic-ischemic neonatal rats. FASEB J. 2022 Apr;36(4):e22263. doi: 10.1096/fj.202101654RR. [Accessed 15 Jun. 2024] Available at: