Abevmy 400mg Injection

Introduction

Abevmy is a prescription medication that contains the active ingredient bevacizumab. It is available under the brand name Abevmy. Bevacizumab is a type of medication known as a monoclonal antibody, which is used in the treatment of certain types of cancer.

Uses

Abevmy is primarily used in the treatment of various types of cancer. It is commonly prescribed for:

• Colorectal cancer
• Lung cancer (non-small cell)
• Glioblastoma (a type of brain cancer)
• Kidney cancer (renal cell carcinoma)
• Cervical cancer
• Ovarian cancer

Please note that Abevmy should only be used under the supervision of a healthcare professional experienced in the administration of anticancer medications.

Dosage and Administration

Abevmy is administered intravenously (into a vein) by a healthcare professional. The dosage and schedule of administration may vary based on the specific type of cancer being treated and other individual factors. Your healthcare provider will determine the appropriate dose and treatment schedule for you.

Mechanism of Action

Bevacizumab, the active ingredient in Abevmy, works by inhibiting the growth of new blood vessels. In cancer, tumors need a blood supply to grow and spread. Bevacizumab targets a protein called vascular endothelial growth factor (VEGF), which plays a key role in the formation of new blood vessels. By blocking VEGF, bevacizumab helps to inhibit the growth of blood vessels in the tumor, thereby reducing its blood supply and potentially slowing its growth.

Side Effects

Common side effects may include:

• Fatigue
• High blood pressure
• Headache
• Nosebleeds
• Loss of appetite
• Diarrhea
• Nausea
• Vomiting

These side effects are usually temporary and can be managed with appropriate medical care. However, contact your healthcare provider if you experience any severe or persistent side effects.

Serious side effects that may rarely occur with Abevmy include:

• Severe bleeding or hemorrhage
• Blood clots
• Heart problems
• Kidney problems
• Gastrointestinal perforation (a hole or tear in the stomach or intestines)

If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Abevmy may interact with certain medications, including:

• Anticoagulants (blood thinners) such as warfarin
• Antiplatelet medications such as aspirin
• Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen

inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, and herbal products, to avoid potential interactions.

Precautions

Before using Abevmy, inform your healthcare provider about any pre-existing medical conditions or allergies you may have. Additionally, let them know about any other medications or supplements you are taking.

Abevmy is not recommended for use in certain situations, including:

• Pregnancy: Abevmy may cause harm to an unborn baby. Discuss the potential risks and benefits with your healthcare provider if you are pregnant or planning to become pregnant.
• Breastfeeding: It is not known whether Abevmy passes into breast milk. Consult your healthcare provider if you are breastfeeding or planning to breastfeed.
• Hypersensitivity: If you have had an allergic reaction to bevacizumab or any other ingredients in Abevmy, inform your healthcare provider before using this medication.

Storage

Abevmy should be stored in a refrigerator between 2°C and 8°C (36°F and 46°F). Do not freeze the medication. Keep it in its original packaging and protect it from light.

Patient Tips

• Follow the instructions provided by your healthcare provider for the proper administration of Abevmy.
• Keep all scheduled appointments with your healthcare provider to ensure regular monitoring of your condition.
• Report any side effects or concerns to your healthcare provider promptly.
• Do not use Abevmy if the packaging is damaged or if the medication has expired.
• Store the medication out of the reach of children and pets.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Alymsys 25mg/ml concentrate for solution for infusion (Health Professionals SmPC) Available at:
• Bevacizumab (Drugs.com) [Accessed 4 Jun. 2024] (online) Available at:
• bevacizumab solution (RX) [Accessed 22 Jun. 2024] (online) Available at:
• Bevacizumab Injection (MedlinePlus) [Accessed 7 Jun. 2024] (online) Available at:
• Garcia J, Hurwitz HI, Sandler AB, Miles D, Coleman RL, Deurloo R, Chinot OL. Bevacizumab (Avastin) in cancer treatment: A review of 15 years of clinical experience and future outlook. Cancer Treat Rev. 2020 Jun;86:102017. doi: 10.1016/j.ctrv.2020.102017. Epub 2020 Mar 26. [Accessed 26 Jun. 2024] Available at: