Abiracure 500mg Tablet

Introduction

Abiracure is a prescription medication that contains Abiraterone Acetate as its active ingredient. It is available in tablet form and is primarily used in the treatment of certain types of advanced prostate cancer.

Uses

Abiracure is prescribed to patients who have been diagnosed with metastatic castration-resistant prostate cancer (mCRPC). It is specifically indicated for use in combination with prednisone or prednisolone.

Dosage and Administration

The dosage of Abiracure may vary depending on individual patient factors and the specific treatment plan recommended by the healthcare provider. Carefully follow the instructions provided by your healthcare professional.

Generally, Abiracure is taken orally once a day on an empty stomach, at least one hour before or two hours after a meal. The tablets should be swallowed whole with water and should not be crushed, chewed, or broken.

Mechanism of Action

Abiraterone Acetate, the active ingredient in Abiracure, belongs to a class of medications known as androgen biosynthesis inhibitors. It works by inhibiting an enzyme called CYP17, which is involved in the production of androgens (male hormones) in the body, including testosterone.

By blocking the production of androgens, Abiracure helps slow down the growth of prostate cancer cells and may also reduce the symptoms associated with the disease.

Side Effects

Common side effects may include fatigue, joint pain, swelling in the legs or feet, hot flashes, diarrhea, and high blood pressure.

In some cases, more serious side effects may occur. These can include liver problems, fluid retention, cardiac disorders, adrenal insufficiency, and allergic reactions. If you experience any of these serious side effects or any other unusual symptoms, seek medical attention immediately.

Drug Interactions

Abiracure may interact with other medications, including over-the-counter drugs, herbal supplements, and vitamins. Inform your healthcare provider about all the medications you are currently taking to avoid any potential drug interactions.

Some medications that may interact with Abiracure include certain anticoagulants, anti-arrhythmics, and medications that are metabolized by the liver. Your healthcare provider will be able to provide specific guidance on potential drug interactions and adjust your treatment plan accordingly.

Precautions

Before starting treatment with Abiracure, inform your healthcare provider about any existing medical conditions or allergies you may have. This medication may not be suitable for individuals with certain liver problems or those who have a history of adrenal insufficiency.

Abiracure may also interact with certain medications, including strong CYP3A4 inhibitors and inducers, so disclose all medications you are currently taking.

Storage

Abiracure should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Take Abiracure exactly as prescribed by your healthcare provider.
• Do not stop taking the medication without consulting your doctor, as this may affect the effectiveness of the treatment.
• If you miss a dose, take it as soon as you remember, unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule.
• Inform your healthcare provider about any side effects or unusual symptoms you experience while taking Abiracure.
• Follow any additional instructions provided by your healthcare provider regarding diet, lifestyle, or other medications that may affect the treatment.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• About medroxyprogesterone tablets (NHS UK) [Accessed 9 Jun. 2024] (online) Available at:
• Abiraterone 250 mg film-coated tablet (Health Professionals SmPC) Available at:
• Abiraterone (Drugs.com) [Accessed 6 Jun. 2024] (online) Available at:
• abiraterone acetate (RX) [Accessed 5 Jun. 2024] (online) Available at:
• Drugs Approved for Prostate Cancer (National Cancer Institute) [Accessed 14 Jun. 2024] (online) Available at:
• Chi KN, Rathkopf D, Smith MR, Efstathiou E, Attard G, Olmos D, Lee JY, Small EJ, Pereira de Santana Gomes AJ, Roubaud G, Saad M, Zurawski B, Sakalo V, Mason GE, Francis P, Wang G, Wu D, Diorio B, Lopez-Gitlitz A, Sandhu S; MAGNITUDE Principal Investigators. Niraparib and Abiraterone Acetate for Metastatic Castration-Resistant Prostate Cancer. J Clin Oncol. 2023 Jun 20;41(18):3339-3351. doi: 10.1200/JCO.22.01649. Epub 2023 Mar 23. [Accessed 5 Jun. 2024] Available at: