Acaya 100mg Tablet

Introduction

Acaya is a prescription medication that contains the active ingredient Acalabrutinib. It is available in tablet form and is commonly used to treat certain types of cancer, specifically chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). Acaya helps to inhibit the growth and spread of cancer cells, providing relief and improved quality of life for patients.

Uses

Acaya is primarily prescribed to treat chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). These are types of cancers that affect the blood and lymphatic system. By targeting specific proteins involved in the growth and survival of cancer cells, Acaya helps to slow down the progression of the disease and improve overall outcomes for patients.

Dosage and Administration

The dosage of Acaya will vary depending on the individual patient and their specific condition. Follow the instructions provided by your healthcare provider or pharmacist. Typically, Acaya is taken orally once or twice daily, with or without food. Swallow the tablet whole with a glass of water, and do not crush or chew it. If you have difficulty swallowing tablets, talk to your healthcare provider about alternative options.

Mechanism of Action

Acaya belongs to a class of medications called Bruton’s tyrosine kinase (BTK) inhibitors. It works by specifically targeting and blocking the activity of BTK, a protein that plays a crucial role in the survival and growth of cancer cells. By inhibiting BTK, Acaya helps to disrupt the signaling pathways that promote cancer cell growth, ultimately leading to a reduction in tumor size and improved disease control.

Side Effects

Common side effects may include headache, fatigue, diarrhea, nausea, and muscle pain. These side effects are generally mild and temporary, but if they persist or worsen, consult your healthcare provider.

In rare cases, Acaya may cause more serious side effects, such as bleeding problems, infections, or heart rhythm abnormalities. If you experience any unusual bleeding, signs of infection (such as fever or persistent sore throat), or irregular heartbeats, seek medical attention immediately.

Drug Interactions

inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Certain medications may interact with Acaya and affect its effectiveness or increase the risk of side effects. Some common and serious drug interactions with Acaya include:

• Strong CYP3A inhibitors (e.g., ketoconazole, clarithromycin) may increase the concentration of Acaya in the body, leading to an increased risk of side effects.
• Strong CYP3A inducers (e.g., rifampin, carbamazepine) may decrease the concentration of Acaya, reducing its effectiveness.

Discuss all potential drug interactions with your healthcare provider to ensure the safe and effective use of Acaya.

Precautions

Before starting treatment with Acaya, inform your healthcare provider about any pre-existing medical conditions or allergies you may have. Additionally, discuss any other medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements.

Acaya may not be suitable for everyone. It is contraindicated in patients with known hypersensitivity to Acalabrutinib or any of the ingredients in the formulation. Note that Acaya may interact with certain medications, such as strong CYP3A inhibitors or inducers, as mentioned in the previous section.

Storage

Acaya should be stored at room temperature, away from direct sunlight and moisture. Keep the medication in its original packaging and out of reach of children and pets. Do not use Acaya beyond its expiration date, as it may no longer be effective.

Patient Tips

• Follow your healthcare provider’s instructions regarding the dosage and administration of Acaya. Take the medication as prescribed and at the same time each day to maintain consistent levels in your body.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule.
• Do not stop taking Acaya without consulting your healthcare provider. Discontinuing the medication without medical guidance may affect its effectiveness and potentially worsen your condition.
• attend all scheduled appointments with your healthcare provider for regular check-ups and monitoring.
• If you have any concerns or questions about Acaya or its use, do not hesitate to consult your healthcare provider. They are the best resource for personalized advice and guidance based on your individual circumstances.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Acalabrutinib (Drugs.com) [Accessed 3 Jun. 2024] (online) Available at:
• acalabrutinib capsule (RX) [Accessed 26 Jun. 2024] (online) Available at:
• Acalabrutinib (MedlinePlus) [Accessed 21 Jun. 2024] (online) Available at:
• Byrd JC, Hillmen P, Ghia P, Kater AP, Chanan-Khan A, Furman RR, O’Brien S, Yenerel MN, Illés A, Kay N, Garcia-Marco JA, Mato A, Pinilla-Ibarz J, Seymour JF, Lepretre S, Stilgenbauer S, Robak T, Rothbaum W, Izumi R, Hamdy A, Patel P, Higgins K, Sohoni S, Jurczak W. Acalabrutinib Versus Ibrutinib in Previously Treated Chronic Lymphocytic Leukemia: Results of the First Randomized Phase III Trial. J Clin Oncol. 2021 Nov 1;39(31):3441-3452. doi: 10.1200/JCO.21.01210. Epub 2021 Jul 26. [Accessed 8 Jun. 2024] Available at: