Acec R Plus 200mg/20mg Tablet

Introduction

Acec R Plus is a prescription medication that combines two active ingredients: Aceclofenac and Rabeprazole. Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that helps reduce pain and inflammation, while Rabeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production. This combination medication is primarily used to treat pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

Uses

Acec R Plus is prescribed to relieve pain and reduce inflammation in various conditions, including:

• Osteoarthritis: A degenerative joint disease that causes joint pain and stiffness.
• Rheumatoid arthritis: An autoimmune disease that affects the joints, causing pain, swelling, and stiffness.
• Ankylosing spondylitis: A type of arthritis that primarily affects the spine, leading to pain and stiffness in the back and neck.

This medication helps alleviate symptoms such as joint pain, swelling, and stiffness, allowing patients to maintain their daily activities with greater ease.

Dosage and Administration

follow the dosage instructions provided by your healthcare professional. The usual recommended dosage of Acec R Plus is one tablet taken orally once daily, preferably with food. Swallow the tablet whole with a glass of water, without crushing, chewing, or breaking it.

Your healthcare professional may adjust the dosage based on your medical condition and response to treatment. Take the medication as prescribed and not exceed the recommended dosage.

Mechanism of Action

Acec R Plus contains two active ingredients with different mechanisms of action:

• Aceclofenac: It works by inhibiting the production of certain chemicals in the body called prostaglandins, which are responsible for pain and inflammation. By reducing the levels of these chemicals, Aceclofenac helps relieve pain and inflammation in the joints.
• Rabeprazole: It belongs to a class of medications called proton pump inhibitors (PPIs). Rabeprazole works by reducing the production of stomach acid, which is beneficial for patients who may experience stomach irritation or ulcers due to the use of NSAIDs like Aceclofenac.

By combining these two medications, Acec R Plus provides a dual-action approach to alleviate pain, reduce inflammation, and protect the stomach from potential side effects.

Side Effects

Common side effects may include:

• Upset stomach
• Nausea
• Diarrhea
• Headache
• Dizziness

These side effects are usually mild and temporary, but if they persist or worsen, consult your healthcare professional.

In rare cases, Acec R Plus may cause more serious side effects. Contact your healthcare professional immediately if you experience any of the following:

• Severe stomach pain
• Black, tarry stools
• Vomiting blood
• Allergic reactions such as rash, itching, swelling, or difficulty breathing

Drug Interactions

inform your healthcare professional about all the medications you are currently taking, including prescription, over-the-counter drugs, and herbal supplements. Acec R Plus may interact with certain medications, including:

• Anticoagulants (blood thinners)
• Antiplatelet drugs
• Diuretics
• Methotrexate
• Antidepressants
• Corticosteroids

These are not the only possible drug interactions, so provide a comprehensive list of your medications to your healthcare professional to avoid potential interactions.

Precautions

Before taking Acec R Plus, consider the following precautions:

• Allergies: If you are allergic to Aceclofenac, Rabeprazole, or any other NSAIDs or PPIs, inform your healthcare professional.
• Stomach ulcers or bleeding: Inform your healthcare professional if you have a history of stomach ulcers or bleeding.
• Pregnancy and breastfeeding: Consult your healthcare professional before using Acec R Plus if you are pregnant, planning to become pregnant, or breastfeeding.
• Medical conditions: Inform your healthcare professional about any underlying medical conditions, such as liver or kidney disease, high blood pressure, or heart disease.

Storage

Store Acec R Plus at room temperature, away from direct sunlight and moisture. Keep it out of the reach of children and pets. Do not use the medication beyond its expiration date.

Patient Tips

• Take Acec R Plus with food to help reduce the risk of stomach upset.
• Avoid consuming alcohol while taking this medication, as it may increase the risk of stomach irritation.
• If you forget to take a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not share your medication with others, as it is prescribed specifically for your condition.
• If you have any concerns or questions about your medication, consult your healthcare professional for further guidance. They are the best source of information tailored to your specific needs.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Rabeprazole: medicine to lower stomach acid (NHS UK) [Accessed 30 Jun. 2024] (online) Available at:
• Aceclofenac 100 mg Film-coated Tablets (Health Professionals SmPC) Available at:
• ACECLOFENAC 100MG TABLETS (Drugs.com) [Accessed 11 Jun. 2024] (online) Available at:
• rabeprazole sodium (RX) [Accessed 26 Jun. 2024] (online) Available at:
• Rabeprazole (MedlinePlus) [Accessed 30 Jun. 2024] (online) Available at:
• Negi S, Tandel N, Sharma P, Kumar R, Tyagi RK. Aceclofenac and methotrexate combination therapy could influence Th1/Th17 axis to modulate rheumatoid-arthritis-induced inflammation. Drug Discov Today. 2023 Aug;28(8):103671. doi: 10.1016/j.drudis.2023.103671. Epub 2023 Jun 16. [Accessed 25 Jun. 2024] Available at: