Acefe SP Tablet

Introduction

Acefe SP is a prescription medication that combines three active ingredients: Aceclofenac, Paracetamol, and Serratiopeptidase. It is commonly used to relieve pain and reduce inflammation associated with various conditions.

Uses

Acefe SP is primarily prescribed for the management of pain and inflammation caused by conditions such as arthritis, sprains, strains, and postoperative discomfort. It can also be used to alleviate pain associated with dental procedures.

Dosage and Administration

The dosage of Acefe SP may vary depending on the severity of the pain and the individual’s response to the medication. Follow the instructions provided by your healthcare professional. Generally, it is recommended to take one tablet orally, with or without food, as prescribed. Avoid crushing or chewing the tablet, and to swallow it whole with a glass of water.

Mechanism of Action

Aceclofenac, one of the active ingredients in Acefe SP, is a nonsteroidal anti-inflammatory drug (NSAID). It works by inhibiting the production of certain chemicals in the body that cause pain and inflammation. Paracetamol, another active ingredient, helps to reduce pain and fever. Serratiopeptidase, the third active ingredient, is an enzyme that has anti-inflammatory properties and helps to break down certain proteins in the body, reducing swelling.

Side Effects

Common side effects may include nausea, stomach discomfort, headache, and dizziness. These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, such as allergic reactions, difficulty breathing, or signs of bleeding, seek immediate medical attention.

Drug Interactions

Acefe SP may interact with certain medications, including blood thinners, other NSAIDs, and certain antidepressants. Inform your healthcare professional about all the medications you are currently taking, including over-the-counter drugs and herbal supplements, to avoid any potential interactions. They can provide guidance on whether any adjustments in dosage or alternative medications are necessary.

Precautions

Before taking Acefe SP, inform your healthcare professional about any allergies, medical conditions, or medications you are currently taking. This medication may not be suitable for individuals with a history of gastrointestinal ulcers, liver or kidney problems, or bleeding disorders. Avoid alcohol consumption while taking Acefe SP, as it may increase the risk of stomach irritation and liver damage.

Storage

Acefe SP should be stored at room temperature, away from moisture and direct sunlight. Keep it out of reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Take Acefe SP exactly as prescribed by your healthcare professional.
• Do not exceed the recommended dosage or take the medication for a longer duration than advised.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• If you have any concerns or questions about the medication, do not hesitate to reach out to your healthcare professional.
• follow a well-balanced diet, maintain hydration, and exercise regularly while taking this medication.
• If you experience any new or worsening symptoms while taking Acefe SP, consult your healthcare professional for further evaluation.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Paracetamol for adults: painkiller for pain and high temperature (NHS UK) [Accessed 17 Jun. 2024] (online) Available at:
• Aceclofenac 100 mg Film-coated Tablets (Health Professionals SmPC) Available at:
• ACECLOFENAC 100MG TABLETS (Drugs.com) [Accessed 11 Jun. 2024] (online) Available at:
• paracetamol tablet (OTC) [Accessed 9 Jun. 2024] (online) Available at:
• Acetaminophen Level: MedlinePlus Medical Test (MedlinePlus) [Accessed 23 Jun. 2024] (online) Available at: acetaminophen-level” rel=”noreferrer noopener” target=”_blank”>
• Negi S, Tandel N, Sharma P, Kumar R, Tyagi RK. Aceclofenac and methotrexate combination therapy could influence Th1/Th17 axis to modulate rheumatoid-arthritis-induced inflammation. Drug Discov Today. 2023 Aug;28(8):103671. doi: 10.1016/j.drudis.2023.103671. Epub 2023 Jun 16. [Accessed 25 Jun. 2024] Available at: