Introduction
Acistal D is a prescription medication that contains two active ingredients: Domperidone and Rabeprazole. Domperidone is a medication that helps to relieve symptoms of nausea and vomiting, while Rabeprazole belongs to a class of drugs known as proton pump inhibitors, which reduce the amount of acid produced in the stomach. This combination medication is primarily used to treat conditions such as gastroesophageal reflux disease (GERD) and gastric ulcers.
Uses
Acistal D is prescribed for the following conditions:
- Gastroesophageal reflux disease (GERD): a chronic condition in which stomach acid flows back into the esophagus, causing symptoms such as heartburn and regurgitation.
- Gastric ulcers: open sores that develop on the lining of the stomach, often caused by an imbalance of digestive juices.
Dosage and Administration
- The dosage of Acistal D may vary depending on the specific condition being treated and the patient’s individual response to the medication.
- follow the instructions provided by your healthcare provider or pharmacist.
- The tablets should be taken orally, with or without food, as directed.
- Swallow the tablets whole with a glass of water. Do not crush or chew the tablets, as it may affect the release of the medication.
Mechanism of Action
- Domperidone works by blocking dopamine receptors in the brain and gut, which helps to increase the movement of food through the digestive system and prevents nausea and vomiting.
- Rabeprazole works by inhibiting the proton pump in the stomach, which reduces the production of stomach acid and helps to heal and prevent ulcers.
Side Effects
Common side effects of Acistal D may include:
- Headache
- Diarrhea
- Nausea
- Abdominal pain
- Dizziness
Serious side effects are rare but may include:
- Allergic reactions (rash, itching, swelling)
- Irregular heartbeat
- Signs of liver problems (dark urine, yellowing of the skin or eyes, persistent fatigue)
If you experience any of these serious side effects or any other unusual symptoms, seek medical attention immediately.
Drug Interactions
Acistal D may interact with certain medications, including:
- Antifungal medications (such as ketoconazole)
- Antibiotics (such as clarithromycin)
- HIV protease inhibitors (such as ritonavir)
- Warfarin (a blood thinner)
inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter, and herbal products, to avoid potential drug interactions.
Precautions
- Inform your healthcare provider about any allergies you have, especially to Domperidone, Rabeprazole, or any other medications.
- Let your healthcare provider know about any medical conditions you have, especially liver or kidney problems.
- Avoid alcohol consumption while taking this medication, as it may increase the risk of side effects.
- Acistal D may not be suitable for use during pregnancy or breastfeeding. Consult your healthcare provider before using this medication if you are pregnant, planning to become pregnant, or breastfeeding.
Storage
- Store Acistal D at room temperature, away from excessive heat and moisture.
- Keep the medication out of reach of children and pets.
- Do not use the medication if it has expired or if the packaging is damaged.
Patient Tips
- Take Acistal D exactly as prescribed by your healthcare provider. Do not exceed the recommended dosage or use it for a longer duration than instructed.
- If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- If you have any questions or concerns about the medication, consult your healthcare provider or pharmacist.
- It may take some time for Acistal D to provide relief from symptoms. If your symptoms worsen or do not improve after a few weeks of treatment, contact your healthcare provider.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Domperidone: anti-sickness medicine for nausea and vomiting (NHS UK) [Accessed 10 Jun. 2024] (online) Available at:
- Domperidone 10 mg film-coated tablets (Health Professionals SmPC) Available at:
- Domperidone (Drugs.com) [Accessed 4 Jun. 2024] (online) Available at:
- rabeprazole sodium (RX) [Accessed 26 Jun. 2024] (online) Available at:
- Definitions of Digestive Terms (International Foundation for Gastrointestinal Disorders) [Accessed 3 Jun. 2024] (online) Available at:
- Puoti MG, Assa A, Benninga M, Broekaert IJ, Carpi FJM, Deganello Saccomani M, Dolinsek J, Homan M, Mas E, Miele E, Tzivinikos C, Thomson M, Borrelli O. Drugs in Focus: Domperidone. J Pediatr Gastroenterol Nutr. 2023 Aug 1;77(2):e13-e22. doi: 10.1097/MPG.0000000000003822. Epub 2023 May 9. [Accessed 7 Jun. 2024] Available at:
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