Actiglim M 1mg/500mg Tablet

Introduction

Actiglim M is a prescription medication that contains two active ingredients: Glimepiride and Metformin. Glimepiride belongs to a class of drugs called sulfonylureas, while Metformin belongs to the class of medications known as biguanides. Actiglim M is primarily used to treat type 2 diabetes mellitus.

Uses

Actiglim M is prescribed to help control blood sugar levels in individuals with type 2 diabetes. It is used when diet and exercise alone are not sufficient in managing the condition. By improving insulin secretion and reducing insulin resistance, Actiglim M helps lower blood sugar levels and prevents complications associated with diabetes.

Dosage and Administration

The dosage of Actiglim M will vary depending on individual factors such as age, medical history, and response to treatment. Follow the instructions provided by your healthcare provider. Generally, the recommended starting dose for adults is one tablet of Actiglim M once daily, taken with meals. Your doctor may adjust the dosage as needed to achieve optimal blood sugar control.

Mechanism of Action

Glimepiride, one of the active ingredients in Actiglim M, works by stimulating the release of insulin from the pancreas. It helps the body utilize insulin more effectively, thereby reducing blood sugar levels. Metformin, on the other hand, decreases the production of glucose in the liver and improves the body’s response to insulin. Together, these actions help regulate blood sugar levels in patients with type 2 diabetes.

Side Effects

Common side effects may include nausea, diarrhea, stomach upset, and dizziness. These side effects are usually mild and temporary. However, if they persist or worsen. Inform your healthcare provider.

In rare cases, Actiglim M may cause more serious side effects such as low blood sugar (hypoglycemia) or lactic acidosis. Symptoms of low blood sugar may include sweating, trembling, dizziness, confusion, and rapid heartbeat. If you experience any of these symptoms, treat hypoglycemia promptly by consuming a source of glucose such as fruit juice or candy.

Lactic acidosis is a rare but serious condition that can occur with the use of metformin. Symptoms may include muscle pain, weakness, difficulty breathing, and unusual tiredness. If you experience any of these symptoms, seek immediate medical attention.

Drug Interactions

Actiglim M may interact with certain medications, including other antidiabetic drugs, beta-blockers, and certain antibiotics. Inform your healthcare provider about all the medications you are taking, including over-the-counter drugs and herbal supplements, to avoid potential interactions. Your doctor will monitor your medication regimen and adjust the dosages as necessary to minimize the risk of drug interactions.

Precautions

Before taking Actiglim M, inform your healthcare provider about any medical conditions you have, especially kidney or liver problems. This medication may not be suitable for individuals with certain medical conditions or contraindications.

Actiglim M should be used with caution in individuals who are pregnant or breastfeeding. Discuss the potential risks and benefits with your healthcare provider before starting this medication.

Storage

Patient Tips

• Take Actiglim M exactly as prescribed by your healthcare provider. Do not change the dosage or stop taking the medication without consulting your doctor.
• monitor your blood sugar levels regularly as advised by your healthcare provider.
• Follow a healthy diet and exercise regularly to complement the effects of Actiglim M in managing your diabetes.
• Be aware of the signs and symptoms of low blood sugar (hypoglycemia) and seek prompt treatment if necessary.
• Keep an up-to-date list of all your medications and share it with your healthcare provider to avoid potential drug interactions.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Glimepiride: medicine to treat type 2 diabetes (NHS UK) [Accessed 4 Jun. 2024] (online) Available at:
• Glimepiride 1 mg tablets (Health Professionals SmPC) Available at:
• Glimepiride (Drugs.com) [Accessed 6 Jun. 2024] (online) Available at:
• glimepiride (amaryl) (RX) [Accessed 9 Jun. 2024] (online) Available at:
• Glimepiride (MedlinePlus) [Accessed 25 Jun. 2024] (online) Available at:
• Ridderstråle M, Andersen KR, Zeller C, Kim G, Woerle HJ, Broedl UC; EMPA-REG H2H-SU trial investigators. Comparison of empagliflozin and glimepiride as add-on to metformin in patients with type 2 diabetes: a 104-week randomised, active-controlled, double-blind, phase 3 trial. Lancet Diabetes Endocrinol. 2014 Sep;2(9):691-700. doi: 10.1016/S2213-8587(14)70120-2. Epub 2014 Jun 16. [Accessed 3 Jun. 2024] Available at: