Actorab IT 20mg/150mg Tablet

Introduction

Actorab IT is a prescription medication that contains two active ingredients: Rabeprazole and Itopride. Rabeprazole is a proton pump inhibitor (PPI) that helps reduce the production of stomach acid, while Itopride is a prokinetic agent that improves the movement of food through the digestive system.

Uses

Actorab IT is commonly prescribed for the treatment of gastroesophageal reflux disease (GERD), a condition characterized by the backward flow of stomach acid into the esophagus, causing heartburn and acid reflux. It is also used to alleviate symptoms associated with functional dyspepsia, such as stomach pain, bloating, and early satiety.

Dosage and Administration

The recommended dosage of Actorab IT may vary depending on the severity of the condition and individual patient factors. Follow the instructions provided by your healthcare professional or the directions on the prescription label. Typically, the usual adult dosage is one tablet taken orally, twice daily before meals. However, your healthcare professional may adjust the dosage to meet your specific needs.

Mechanism of Action

Actorab IT works by targeting different mechanisms in the digestive system. Rabeprazole helps reduce the production of stomach acid by inhibiting the activity of the proton pump in the stomach lining. This helps alleviate symptoms of GERD and promotes the healing of erosive esophagitis. Itopride, on the other hand, enhances the movement of food through the digestive system by increasing the release of acetylcholine, a neurotransmitter that stimulates gastrointestinal motility. This helps relieve symptoms associated with functional dyspepsia.

Side Effects

Common side effects may include headache, diarrhea, nausea, abdominal pain, and dry mouth. These side effects are usually mild and transient.

However, if you experience any serious side effects such as severe abdominal pain, persistent diarrhea, chest pain, difficulty swallowing, or signs of an allergic reaction (e.g., rash, itching, swelling, severe dizziness), seek medical attention immediately.

Drug Interactions

Actorab IT may interact with other medications, including certain anticoagulants (such as warfarin), antiplatelet drugs (such as clopidogrel), and medications metabolized by the CYP2C19 enzyme (such as diazepam and phenytoin). Inform your healthcare professional about all the medications you are currently taking to avoid potential drug interactions.

Precautions

Before taking Actorab IT, inform your healthcare professional about any medical conditions you have, especially if you have a history of liver disease or if you are pregnant or breastfeeding. Additionally, avoid alcohol consumption while taking this medication, as alcohol may exacerbate certain side effects.

Storage

Actorab IT should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Take Actorab IT exactly as prescribed by your healthcare professional.
• It is generally recommended to take the medication before meals to optimize its effectiveness.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not crush or chew the tablet. Swallow it whole with a glass of water.
• If you have any concerns or questions about your treatment with Actorab IT, don’t hesitate to consult your healthcare professional for guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Rabeprazole: medicine to lower stomach acid (NHS UK) [Accessed 30 Jun. 2024] (online) Available at:
• PARIET 10mg (Health Professionals SmPC) Available at:
• Itopride (International database) (Drugs.com) [Accessed 1 Jun. 2024] (online) Available at:
• rabeprazole sodium (RX) [Accessed 26 Jun. 2024] (online) Available at:
• Rabeprazole (MedlinePlus) [Accessed 30 Jun. 2024] (online) Available at:
• Dzierżanowski T, Kozlowski M. Itopride increases the effectiveness of the management of opioid-induced constipation in palliative care patients: an observational non-interventional study. Arch Med Sci. 2019 Jul 18;18(5):1271-1278. doi: 10.5114/aoms.2019.85943. eCollection 2022. [Accessed 13 Jun. 2024] Available at: