Acuclav 125mg/25mg Injection

Introduction

Acuclav is a prescription medication that contains two active ingredients: Amoxicillin and Clavulanic Acid. It is commonly known by its generic name, Amoxicillin-Clavulanate, and is also available under various brand names. This medication is primarily used to treat bacterial infections.

Uses

Acuclav is prescribed for a range of bacterial infections. Some common conditions it is used to treat include respiratory tract infections, urinary tract infections, skin and soft tissue infections, and intra-abdominal infections. It may also be used in combination with other medications to treat more severe infections.

Dosage and Administration

The dosage of Acuclav will vary depending on the specific infection being treated, the patient’s age, weight, and overall health. It is typically administered by a healthcare professional in a hospital or clinical setting. The injection is given intravenously (into a vein) to ensure effective delivery of the medication.

Mechanism of Action

Acuclav works by combining the actions of two active ingredients, Amoxicillin and Clavulanic Acid. Amoxicillin is an antibiotic that inhibits the growth of bacteria by interfering with the synthesis of their cell walls. Clavulanic Acid is a beta-lactamase inhibitor, which helps to prevent the breakdown of Amoxicillin by certain bacteria, thereby enhancing its effectiveness against a broader range of bacterial strains.

Side Effects

Common side effects may include diarrhea, nausea, vomiting, and allergic reactions such as rash or itching. Notify your healthcare provider if any side effects occur, especially if they are persistent or severe.

Serious side effects are rare but can occur. These may include severe allergic reactions (anaphylaxis), liver problems, and blood disorders. If you experience any unusual symptoms, such as difficulty breathing, yellowing of the skin or eyes, or unusual bleeding or bruising, seek immediate medical attention.

Drug Interactions

Acuclav may interact with certain medications, including other antibiotics, oral contraceptives, and medications that affect the liver. Inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter, and herbal products, to avoid potential interactions. Your healthcare provider will carefully consider any potential drug interactions before prescribing Acuclav.

Precautions

Before using Acuclav, inform your healthcare provider about any known allergies or sensitivities to Amoxicillin, Clavulanic Acid, or any other medications. Additionally, discuss your medical history, especially if you have a history of liver problems or blood disorders. This medication may not be suitable for everyone, and your healthcare provider will assess the risks and benefits before prescribing it.

Acuclav may interact with certain medical conditions or medications, so follow your healthcare provider’s instructions and notify them of any changes in your health or medication regimen.

Storage

Patient Tips

• Follow the prescribed dosage and administration instructions provided by your healthcare provider.
• If you miss a dose, contact your healthcare provider for guidance on how to proceed.
• Complete the full course of treatment, even if you start feeling better before it is finished.
• Inform your healthcare provider about any side effects or allergic reactions you experience.
• If you have any concerns or questions about your medication, don’t hesitate to reach out to your healthcare provider or pharmacist for clarification.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Common questions about co-amoxiclav (NHS UK) [Accessed 13 Jun. 2024] (online) Available at:
• Augmentin Duo 400/57 powder for oral suspension (mixed fruit flavour) (Health Professionals SmPC) Available at:
• Clavulanic Acid (International database) (Drugs.com) [Accessed 15 Jun. 2024] (online) Available at:
• Amoxicillin and Clavulanic Acid (MedlinePlus) [Accessed 9 Jun. 2024] (online) Available at:
• Keij FM, Kornelisse RF, Hartwig NG, van der Sluijs-Bens J, van Beek RHT, van Driel A, van Rooij LGM, van Dalen-Vink I, Driessen GJA, Kenter S, von Lindern JS, Eijkemans M, Stam-Stigter GM, Qi H, van den Berg MM, Baartmans MGA, van der Meer-Kappelle LH, Meijssen CB, Norbruis OF, Heidema J, van Rossem MC, den Butter PCP, Allegaert K, Reiss IKM, Tramper-Stranders GA. Efficacy and safety of switching from intravenous to oral antibiotics (amoxicillin-clavulanic acid) versus a full course of intravenous antibiotics in neonates with probable bacterial infection (RAIN): a multicentre, randomised, open-label, non-inferiority trial. Lancet Child Adolesc Health. 2022 Nov;6(11):799-809. doi: 10.1016/S2352-4642(22)00245-0. Epub 2022 Sep 9. [Accessed 30 Jun. 2024] Available at: