Adglytrol-OT Tablet

Introduction

Adglytrol-OT is a prescription medication that contains the active ingredient Teneligliptin. It is available in tablet form and is primarily used to treat type 2 diabetes mellitus.

Uses

Adglytrol-OT is prescribed to manage high blood sugar levels in patients with type 2 diabetes mellitus. It is used as an adjunct to diet and exercise to improve glycemic control. This medication helps in controlling blood sugar levels by increasing the production of insulin and reducing the amount of glucose produced by the liver.

Dosage and Administration

The dosage of Adglytrol-OT may vary depending on individual patient factors and should be determined by a healthcare professional. It is typically taken orally once a day, with or without food. Follow the instructions provided by your doctor or pharmacist regarding the dose and duration of treatment.

Mechanism of Action

Teneligliptin, the active ingredient in Adglytrol-OT, belongs to a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by inhibiting the enzyme DPP-4, which increases the levels of active incretin hormones. These hormones help stimulate the release of insulin and suppress the production of glucagon, resulting in lower blood sugar levels.

Side Effects

Common side effects may include headache, dizziness, stomach upset, diarrhea, and joint pain. These side effects are usually mild and should resolve on their own. However, if they persist or worsen, consult your doctor.

Serious side effects are rare but may include severe allergic reactions, pancreatitis, and liver problems. Seek immediate medical attention if you experience symptoms such as severe rash, itching, difficulty breathing, abdominal pain, or yellowing of the skin and eyes.

Drug Interactions

Adglytrol-OT may interact with other medications, including certain antibiotics, antifungals, and cardiovascular drugs. Inform your doctor about all the medications you are currently taking, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions. Your doctor will be able to determine if any adjustments or precautions are necessary.

Precautions

Before starting Adglytrol-OT, inform your doctor about any medical conditions you have, especially if you have a history of pancreatitis, liver disease, or kidney problems. This medication may not be suitable for everyone, and your doctor will consider your medical history and overall health before prescribing it.

Adglytrol-OT should not be used in patients with type 1 diabetes mellitus, diabetic ketoacidosis, or a known hypersensitivity to Teneligliptin or any other components of the medication.

Storage

Patient Tips

• Take Adglytrol-OT exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider.
• Follow a healthy diet and exercise regularly while taking Adglytrol-OT to help manage your blood sugar levels effectively.
• Monitor your blood sugar regularly as instructed by your doctor and report any significant changes or concerns.
• If you experience any unusual or persistent side effects, contact your doctor immediately.
• Attend regular check-ups with your healthcare provider to monitor your response to the medication and adjust treatment if necessary.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Sharma SK, Panneerselvam A, Singh KP, Parmar G, Gadge P, Swami OC. Teneligliptin in management of type 2 diabetes mellitus. Diabetes Metab Syndr Obes. 2016 Aug 16;9:251-60. doi: 10.2147/DMSO.S106133. eCollection 2016. [Accessed 13 Jun. 2024] Available at:
• Pelluri R, Kongara S, Nagasubramanian VR, Mahadevan S, Chimakurthy J. Systematic review and meta-analysis of teneligliptin for treatment of type 2 diabetes. J Endocrinol Invest. 2023 May;46(5):855-867. doi: 10.1007/s40618-023-02003-9. Epub 2023 Jan 9. [Accessed 19 Jun. 2024] Available at:
• Sharma S, Sharma R, Hatware K, Patil K. Review on Chemistry, Analysis and Pharmacology of Teneligliptin: A Novel DPP-4 Inhibitor. Mini Rev Med Chem. 2020;20(12):1091-1100. doi: 10.2174/1389557520666200228144148. [Accessed 9 Jun. 2024] Available at:
• Abubaker M, Mishra P, Swami OC. Teneligliptin in Management of Diabetic Kidney Disease: A Review of Place in Therapy. J Clin Diagn Res. 2017 Jan;11(1):OE05-OE09. doi: 10.7860/JCDR/2017/25060.9228. Epub 2017 Jan 1. [Accessed 0 Jun. 2024] Available at: