Admine 100 Tablet

Introduction

Admine is a prescription medication that contains the active ingredient Imatinib mesylate. It is available under the brand name Admine. This medication is primarily used in the treatment of certain types of cancers, including chronic myeloid leukemia (CML), acute lymphoblastic leukemia (ALL), and gastrointestinal stromal tumors (GISTs).

Uses

Admine is prescribed to manage and treat the following conditions:

• Chronic myeloid leukemia (CML): This medication helps control the growth of cancer cells in the bone marrow, preventing them from spreading to other parts of the body.
• Acute lymphoblastic leukemia (ALL): Admine is used in combination with other medications to treat ALL, a type of blood cancer that affects the white blood cells.
• Gastrointestinal stromal tumors (GISTs): It is also indicated for the treatment of GISTs, a rare type of tumor that occurs in the digestive tract.

Dosage and Administration

• Dosage: The dosage of Admine may vary depending on the specific condition being treated, the patient’s weight, and other factors. Follow the dosage instructions provided by your healthcare provider. Do not change the dosage or stop taking the medication without consulting your doctor.
• Administration: Admine should be taken orally with a glass of water, with or without food. Swallow the tablet whole, without crushing or chewing it.

Mechanism of Action

Admine contains Imatinib mesylate, which belongs to a class of medications called tyrosine kinase inhibitors. It works by inhibiting the abnormal protein produced by cancer cells, preventing their growth and division. By targeting specific molecules involved in cancer cell growth, Admine helps to slow down or stop the progression of the disease.

Side Effects

Common side effects include:

• Nausea and vomiting
• Diarrhea
• Muscle cramps
• Fatigue
• Skin rash or itching

Serious side effects may occur in rare cases. If you experience any of the following, seek immediate medical attention:

• Difficulty breathing or chest pain
• Unusual bleeding or bruising
• Severe stomach pain
• Yellowing of the skin or eyes (jaundice)
• Swelling of the face, lips, tongue, or throat

If you have any concerns about the side effects, discuss them with your healthcare provider.

Drug Interactions

Admine may interact with other medications, including over-the-counter drugs and herbal supplements. Inform your doctor about all the medications you are currently taking to avoid potential interactions. Some common drug interactions with Admine include:

• Warfarin: Admine may increase the risk of bleeding when taken with warfarin or other blood-thinning medications.
• St. John’s Wort: This herbal supplement may decrease the effectiveness of Admine.
• Antacids: Taking antacids with Admine may reduce the absorption of the medication.

Consult your healthcare provider or pharmacist for a complete list of potential drug interactions.

Precautions

Before starting treatment with Admine, consider the following precautions:

• Contraindications: Admine should not be used in patients who are allergic to Imatinib mesylate or any other components of the medication. It is also contraindicated in pregnant women.
• Other Medications: Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements.
• Liver and Kidney Function: Admine may affect liver and kidney function. Regular monitoring of liver and kidney function tests may be necessary during treatment.
• Pregnancy and Breastfeeding: Admine is not recommended for use during pregnancy or breastfeeding. It may harm the unborn baby or pass into breast milk.

Discuss any existing medical conditions or concerns with your healthcare provider before starting treatment with Admine.

Storage

Admine should be stored at room temperature, away from direct sunlight and moisture. Keep the medication in its original packaging and out of the reach of children. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

Here are some additional tips for patients using Admine:

• Take the medication exactly as prescribed by your healthcare provider. Do not skip doses or alter the dosage without consulting your doctor.
• If you experience persistent or severe side effects, notify your healthcare provider promptly.
• Keep a record of your side effects and any changes in your condition to discuss with your doctor during follow-up appointments.
• Attend all scheduled appointments and laboratory tests as recommended by your healthcare provider to monitor your response to the medication.
• Inform your healthcare provider about any other medications or supplements you are taking, as they may interact with Admine.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Mastocytosis – Treatment (NHS UK) [Accessed 23 Jun. 2024] (online) Available at:
• Imatinib (Drugs.com) [Accessed 18 Jun. 2024] (online) Available at:
• imatinib mesylate (RX) [Accessed 29 Jun. 2024] (online) Available at:
• Imatinib (MedlinePlus) [Accessed 18 Jun. 2024] (online) Available at:
• Penn EH, Chung HJ, Keller M. Imatinib mesylate-induced lichenoid drug eruption. Cutis. 2017 Mar;99(3):189-192. [Accessed 30 Jun. 2024] Available at: