Afdethro Cream

Introduction

Afdethro is a topical medication that contains the active ingredient Erythromycin. It is available in cream form and is primarily used for the treatment of skin infections caused by certain types of bacteria.

Uses

Afdethro is prescribed to treat a variety of skin conditions, including acne vulgaris, folliculitis, and erythrasma. It is also effective in managing superficial skin infections, such as impetigo and infected wounds.

Dosage and Administration

Before applying Afdethro, clean and dry the affected area thoroughly. Take a small amount of cream and gently massage it into the skin until it is evenly distributed. The cream should be applied two to three times daily, or as directed by your healthcare professional. Follow the prescribed dosage and duration of treatment.

Mechanism of Action

Erythromycin, the active ingredient in Afdethro, is an antibiotic that belongs to the macrolide class. It works by inhibiting the growth of bacteria, thus preventing the spread of infection. Erythromycin achieves this by binding to the 50S subunit of the bacterial ribosome, which interferes with protein synthesis and ultimately leads to bacterial cell death.

Side Effects

Common side effects may include mild skin irritation, redness, itching, or a burning sensation at the application site. These side effects are usually temporary and subside on their own.

However, if you experience any severe or persistent side effects, such as severe skin rash, swelling, or difficulty breathing, seek immediate medical attention.

Drug Interactions

Afdethro may interact with certain medications, so inform your healthcare professional about all the medications you are currently taking. Specifically, avoid concomitant use of Afdethro with other topical medications that contain erythromycin or other macrolide antibiotics, as this may increase the risk of adverse effects.

Precautions

Before using Afdethro, inform your healthcare professional if you have any known allergies to erythromycin or other macrolide antibiotics. Additionally, let your healthcare professional know about any other medical conditions you have, especially if you have a history of liver disease or have a weakened immune system.

Avoid contact with the eyes, mouth, nose, or any mucous membranes when applying Afdethro. If accidental contact occurs, rinse thoroughly with water.

Storage

Afdethro should be stored at room temperature, away from direct sunlight and heat sources. Keep the cream out of the reach of children and pets. Do not freeze the cream, and discard any unused medication after the recommended duration of treatment.

Patient Tips

• Follow the dosage instructions provided by your healthcare professional and complete the full course of treatment, even if your symptoms improve.
• Avoid applying Afdethro to broken or damaged skin, as this may increase the risk of systemic absorption and adverse effects.
• If you experience any severe or persistent side effects, contact your healthcare professional.
• Do not share Afdethro with others, as it is prescribed specifically for your condition.
• If you miss a dose, apply it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• If you have any concerns or questions about the use of Afdethro, consult your healthcare professional for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Erythromycin: antibiotic to treat infections (NHS UK) [Accessed 8 Jun. 2024] (online) Available at:
• Aknemycin Plus (Health Professionals SmPC) Available at:
• Erythromycin (Drugs.com) [Accessed 13 Jun. 2024] (online) Available at:
• erythromycin (RX) [Accessed 15 Jun. 2024] (online) Available at:
• Erythromycin (MedlinePlus) [Accessed 1 Jun. 2024] (online) Available at:
• Brittain DC. Erythromycin. Med Clin North Am. 1987 Nov;71(6):1147-54. doi: 10.1016/s0025-7125(16)30802-1. [Accessed 10 Jun. 2024] Available at: