Agoprex Tablet

Introduction

Agoprex is a prescription medication that contains the active ingredient Agomelatine. It is available under the brand name Agoprex. This medication is primarily used to treat major depressive disorder (MDD) in adults.

Uses

Agoprex is prescribed to individuals diagnosed with major depressive disorder (MDD). It is specifically indicated for the treatment of depressive episodes associated with this condition in adults.

Dosage and Administration

The recommended dosage of Agoprex is 25 mg taken orally once daily, preferably at bedtime. Your healthcare provider will determine the appropriate dosage for you based on your individual needs and response to the medication. Follow the prescribed dosage instructions carefully.

Mechanism of Action

Agomelatine, the active ingredient in Agoprex, works by acting as an agonist for melatonin receptors and as an antagonist for serotonin 5-HT2C receptors. By modulating these receptors in the brain, Agomelatine helps to restore the balance of certain chemicals that may be disrupted in individuals with major depressive disorder (MDD).

Side Effects

Common side effects that have been reported with Agomelatine include:

• Headache
• Nausea
• Diarrhea
• Dizziness
• Fatigue
• Insomnia

note that not everyone will experience these side effects, and they may vary in severity. If you experience any persistent or bothersome side effects, it is recommended that you consult your healthcare provider. In rare cases, Agoprex may cause serious side effects such as liver function abnormalities. If you notice any signs of liver problems, such as yellowing of the skin or eyes, dark urine, or persistent nausea, seek immediate medical attention.

Drug Interactions

Agoprex may interact with certain medications, potentially affecting their efficacy or increasing the risk of side effects. Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some common drug interactions with Agomelatine include:

• Monoamine oxidase inhibitors (MAOIs)
• CYP1A2 inhibitors (e.g., fluvoxamine)
• CYP3A4 inhibitors (e.g., ketoconazole)
• Other medications that affect the liver

follow your healthcare provider’s guidance and inform them of any changes in your medication regimen to ensure safe and effective treatment.

Precautions

Before starting treatment with Agoprex. Inform your healthcare provider about any pre-existing medical conditions or allergies you may have. Additionally, certain precautions should be taken into consideration, including:

• Contraindications: Agoprex should not be used in individuals with severe liver impairment or certain rare hereditary conditions.
• Interactions with other medications: Agoprex may interact with other medications, as mentioned in the previous section. Inform your healthcare provider about all medications you are taking to avoid any potential interactions.
• Pregnancy and breastfeeding: The safety of Agoprex during pregnancy and breastfeeding has not been established. Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.

Storage

Patient Tips

• Take Agoprex at the same time every day, preferably at bedtime, unless otherwise instructed by your healthcare provider.
• It may take several weeks before you experience the full benefits of Agoprex. Continue taking the medication as prescribed, even if you start feeling better.
• attend regular follow-up appointments with your healthcare provider to monitor your progress and discuss any concerns or side effects.
• Avoid consuming alcohol while taking Agoprex, as it may increase the risk of side effects.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Agomelatine Aristo 25mg film-coated tablets (Health Professionals SmPC) Available at:
• Agomelatine use while Breastfeeding (Drugs.com) [Accessed 19 Jun. 2024] (online) Available at:
• LactMed: Drugs and Lactation Database (National Library of Medicine) [Accessed 16 Jun. 2024] (online) Available at:
• Norman TR, Olver JS. Agomelatine for depression: expanding the horizons? Expert Opin Pharmacother. 2019 Apr;20(6):647-656. doi: 10.1080/14656566.2019.1574747. Epub 2019 Feb 13. [Accessed 1 Jun. 2024] Available at: