Introduction
Alfenac is a prescription medication that contains two active ingredients: Aceclofenac and Rabeprazole. It is available in the form of extended-release tablets.
Uses
Alfenac is primarily prescribed for the management of pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and dental pain. Additionally, it is also used to reduce the risk of gastric ulcers in patients who are at risk of developing them while taking nonsteroidal anti-inflammatory drugs (NSAIDs).
Dosage and Administration
The dosage of Alfenac may vary depending on the severity of the condition and the individual patient’s response to the medication. Follow the instructions provided by your healthcare professional. The tablet should be taken orally with a glass of water, preferably with food, to reduce the risk of stomach upset. Swallow the tablet whole without crushing or chewing it.
Mechanism of Action
Aceclofenac, one of the active ingredients in Alfenac, belongs to the class of medications known as nonsteroidal anti-inflammatory drugs (NSAIDs). It works by reducing the production of certain chemicals in the body that cause pain and inflammation. Rabeprazole, on the other hand, is a proton pump inhibitor that reduces the production of stomach acid, thereby helping to prevent the formation of gastric ulcers.
Side Effects
Common side effects may include nausea, stomach pain, indigestion, diarrhea, and headache. These side effects are usually mild and go away on their own. However, if you experience any severe or persistent side effects, such as severe stomach pain, black or tarry stools, or signs of an allergic reaction (e.g., rash, itching, swelling), you should seek immediate medical attention.
Drug Interactions
Alfenac may interact with certain medications, including but not limited to other NSAIDs, blood thinners, selective serotonin reuptake inhibitors (SSRIs), and corticosteroids. Inform your healthcare professional about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements, to avoid potential drug interactions.
Precautions
Before taking Alfenac, inform your healthcare professional if you have a history of stomach ulcers or bleeding, liver or kidney problems, high blood pressure, or any other medical conditions. This medication should be used with caution in elderly patients and those with a history of heart disease. Avoid alcohol consumption while taking Alfenac, as it may increase the risk of stomach bleeding.
Storage
Alfenac should be stored at room temperature, away from direct sunlight and moisture. Keep it out of the reach of children and pets. Do not use this medication after the expiration date printed on the packaging.
Patient Tips
- Take Alfenac as directed by your healthcare professional.
- If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- Do not exceed the recommended dosage, as it may increase the risk of side effects.
- If you have any concerns or questions about the medication, consult your healthcare professional for further guidance.
- attend regular follow-up appointments with your healthcare professional to monitor your response to the medication and address any concerns.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Rabeprazole: medicine to lower stomach acid (NHS UK) [Accessed 30 Jun. 2024] (online) Available at:
- Aceclofenac 100 mg Film-coated Tablets (Health Professionals SmPC) Available at:
- ACECLOFENAC 100MG TABLETS (Drugs.com) [Accessed 11 Jun. 2024] (online) Available at:
- rabeprazole sodium (RX) [Accessed 26 Jun. 2024] (online) Available at:
- Rabeprazole (MedlinePlus) [Accessed 30 Jun. 2024] (online) Available at:
- Negi S, Tandel N, Sharma P, Kumar R, Tyagi RK. Aceclofenac and methotrexate combination therapy could influence Th1/Th17 axis to modulate rheumatoid-arthritis-induced inflammation. Drug Discov Today. 2023 Aug;28(8):103671. doi: 10.1016/j.drudis.2023.103671. Epub 2023 Jun 16. [Accessed 25 Jun. 2024] Available at:
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