Alfuprost D 10mg/0.5mg Tablet

Introduction

Alfuprost D is a prescription medication that combines two active ingredients: Alfuzosin and Dutasteride. It is commonly used for the treatment of certain conditions related to the prostate gland in men.

Uses

Alfuprost D is primarily prescribed to address two specific conditions:

• Benign Prostatic Hyperplasia (BPH): Also known as an enlarged prostate, BPH is a common condition in older men. Alfuprost D helps to relieve symptoms such as difficulty urinating, weak urine flow, and frequent urination caused by an enlarged prostate.
• Lower Urinary Tract Symptoms (LUTS): This medication can also be used to alleviate the bothersome urinary symptoms associated with BPH, such as urgency and nocturia (frequent urination during the night).

Dosage and Administration

follow the dosage instructions provided by your healthcare provider. Typically, the recommended dosage of Alfuprost D is one tablet taken orally daily, preferably after a meal. The tablet should be swallowed whole with a glass of water, without crushing or chewing it.

Mechanism of Action

Alfuprost D contains two active ingredients, Alfuzosin and Dutasteride, which work in different ways to address the symptoms of an enlarged prostate:

• Alfuzosin: It belongs to a class of medications called alpha-blockers. Alfuzosin helps to relax the muscles in the prostate and bladder neck, making it easier to urinate.
• Dutasteride: This medication is from a class of drugs known as 5-alpha-reductase inhibitors. Dutasteride works by reducing the production of a hormone called dihydrotestosterone (DHT), which contributes to prostate enlargement. By inhibiting DHT, Dutasteride helps to shrink the prostate gland and alleviate urinary symptoms.

Side Effects

be aware of both common and serious side effects and to seek medical attention if necessary. Common side effects may include but are not limited to:

• Dizziness or lightheadedness
• Headache
• Fatigue
• Stomach upset or nausea
• Nasal congestion or stuffiness

Serious side effects are rare but may include:

• Allergic reactions such as rash, itching, or swelling
• Painful or prolonged erections
• Severe dizziness or fainting
• Chest pain or irregular heartbeat

If you experience any of these serious side effects or any other unusual symptoms, contact your healthcare provider immediately.

Drug Interactions

Alfuprost D may interact with other medications, including over-the-counter drugs and herbal supplements. Inform your healthcare provider about all the medications you are currently taking to avoid potential interactions. Some common and serious drug interactions with Alfuprost D include:

• CYP3A4 Inhibitors: Medications that inhibit the enzyme CYP3A4, such as ketoconazole, erythromycin, and ritonavir, may increase the concentration of Alfuzosin in the blood, leading to an increased risk of side effects.
• Alpha-Blockers: Taking other alpha-blockers alongside Alfuprost D may enhance the blood pressure-lowering effects of Alfuzosin, potentially causing dizziness or fainting.

Consult your healthcare provider or pharmacist before starting or stopping any medications while taking Alfuprost D.

Precautions

Before using Alfuprost D, consider the following precautions:

• Contraindications: This medication is contraindicated in individuals with a known hypersensitivity to Alfuzosin, Dutasteride, or any other ingredient in the tablet.
• Pregnancy and Breastfeeding: Alfuprost D is not intended for use in women, especially those who are pregnant or breastfeeding. It can be harmful to the developing fetus or nursing infant.
• Liver Function: Individuals with liver disease should exercise caution while taking Alfuprost D, as the medication may affect liver function. Regular monitoring of liver enzymes may be necessary.
• Prostate Cancer: Alfuprost D is not indicated for the treatment of prostate cancer. Rule out prostate cancer before starting this medication.

Discuss your medical history and any existing health conditions with your healthcare provider before initiating treatment with Alfuprost D.

Storage

Alfuprost D should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use the tablets beyond the expiration date mentioned on the packaging.

Patient Tips

• Follow the prescribed dosage: Take the medication exactly as directed by your healthcare provider. Do not exceed or skip doses without medical advice.
• Be patient: It may take some time to experience the full benefits of Alfuprost D. Stay consistent with your treatment and give it time to work.
• Regular check-ups: Attend regular follow-up appointments with your healthcare provider to monitor your progress and discuss any concerns or changes in your condition.
• Avoid driving or operating machinery: Alfuprost D may cause dizziness or drowsiness. Exercise caution while driving or performing tasks that require alertness until you know how the medication affects you.
• Keep an updated medication list: Maintain a comprehensive list of all the medications you are taking and share it with your healthcare provider to prevent potential drug interactions.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Alfresed 7.5mg/5ml Syrup (Health Professionals SmPC) Available at:
• Alfuzosin (Drugs.com) [Accessed 9 Jun. 2024] (online) Available at:
• alfuzosin hcl er (RX) [Accessed 2 Jun. 2024] (online) Available at:
• Alfuzosin (MedlinePlus) [Accessed 12 Jun. 2024] (online) Available at:
• [No authors listed] Alfuzosin. 2018 Jan 8. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. [Accessed 10 Jun. 2024] Available at: