Introduction
Alphadol is a prescription medication that contains the active ingredient Alfacalcidol. It is available under the brand name Alphadol. This medication is primarily used for the treatment of certain conditions related to calcium and vitamin D metabolism in the body.
Uses
Alphadol is prescribed for various conditions, including:
- Hypocalcemia (low levels of calcium in the blood)
- Osteoporosis (a condition characterized by weak and brittle bones)
- Renal osteodystrophy (a bone disorder that occurs as a result of kidney disease)
- Hypoparathyroidism (low levels of parathyroid hormone)
- Rickets (a condition that affects bone development in children)
- Osteomalacia (softening of the bones)
note that Alphadol should only be used under the guidance and supervision of a healthcare professional.
Dosage and Administration
The dosage of Alphadol may vary depending on the specific condition being treated and individual patient factors. Follow the instructions provided by your healthcare provider. Generally, the recommended dosage for adults is 0.25 to 1 microgram of Alfacalcidol per day.
Alphadol should be taken orally with or without food. Swallow the capsule whole with a glass of water. Do not crush or chew the capsule unless directed by your healthcare provider.
Mechanism of Action
Alfacalcidol, the active ingredient in Alphadol, is a synthetic form of vitamin D. It helps regulate calcium and phosphate levels in the body, which are essential for maintaining healthy bones and teeth. Alfacalcidol works by increasing the absorption of calcium from the intestines and promoting its utilization in the body.
Side Effects
Common side effects may include:
- Headache
- Nausea
- Vomiting
- Diarrhea
- Stomach pain
- Increased thirst
If you experience any of these side effects and they persist or worsen, consult your healthcare provider.
Serious side effects are rare but may include:
- Signs of an allergic reaction (such as rash, itching, swelling, severe dizziness, or difficulty breathing)
- High blood calcium levels (hypercalcemia), which may manifest as symptoms like increased thirst, frequent urination, constipation, or confusion
If you experience any serious side effects, seek immediate medical attention.
Drug Interactions
Alphadol may interact with other medications, potentially affecting their effectiveness or increasing the risk of side effects. Inform your healthcare provider about all the medications, supplements, and herbal products you are currently taking.
Some common drug interactions with Alphadol include:
- Certain antacids or laxatives containing magnesium or aluminum
- Certain diuretics
- Certain cholesterol-lowering medications
- Certain seizure medications
These are not the only possible drug interactions. Your healthcare provider will have a complete list of medications that may interact with Alphadol.
Precautions
Before taking Alphadol, discuss your medical history and any pre-existing conditions with your healthcare provider. Inform them if you have:
- High levels of calcium in the blood (hypercalcemia)
- Kidney disease
- Liver disease
- Heart disease
- History of kidney stones
Alphadol should be used with caution in these situations.
Avoid taking any other calcium or vitamin D supplements without consulting your healthcare provider.
Storage
Alphadol should be stored at room temperature, away from direct sunlight and moisture. Keep it out of the reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.
Patient Tips
- Follow the dosage instructions provided by your healthcare provider and do not exceed the recommended dose.
- If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding, as the use of Alphadol during pregnancy and breastfeeding should be carefully evaluated.
- Attend regular check-ups and laboratory tests as advised by your healthcare provider to monitor your response to the medication and any potential side effects.
- If you have any concerns or questions about Alphadol or your treatment plan, do not hesitate to reach out to your healthcare provider for clarification.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Alfacalcidol 0.25 microgram soft capsules (Health Professionals SmPC) Available at:
- Alfacalcidol (International database) (Drugs.com) [Accessed 7 Jun. 2024] (online) Available at:
- Ureña-Torres PA, Cozzolino M, Bover J. [Utilization of alfacalcidol and active vitamin D analogs in chronic kidney disease]. Nephrol Ther. 2018 Jun;14(4):189-200. doi: 10.1016/j.nephro.2017.03.003. Epub 2018 Mar 12. [Accessed 26 Jun. 2024] Available at:
- Braftovi and Vitamin D3 Interactions (Drugs.com) [Accessed 6 Jun. 2024] (online) Available at:
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