Alphatram 400mg/80mg Tablet

Introduction

Alphatram is a prescription medication that contains two active ingredients: Sulfamethoxazole and Trimethoprim. It is used to treat certain bacterial infections.

Uses

Alphatram is primarily prescribed for the treatment of various bacterial infections. It is commonly used to treat urinary tract infections, middle ear infections, bronchitis, and traveler’s diarrhea caused by specific bacteria. It works by stopping the growth of bacteria, allowing the body’s immune system to fight off the infection.

Dosage and Administration

Alphatram should be taken exactly as prescribed by your healthcare provider. The dosage and duration of treatment may vary depending on the specific infection being treated and your individual medical condition. Follow your healthcare provider’s instructions and complete the full course of treatment to ensure the infection is fully cleared.

The tablets should be taken orally with a full glass of water, preferably with food to help reduce the chance of stomach upset. Take the medication at evenly spaced intervals to maintain a constant level of the drug in your body. Do not crush or chew the tablets unless directed by your healthcare provider.

Mechanism of Action

Sulfamethoxazole and Trimethoprim, the active ingredients in Alphatram, work together to inhibit the growth of bacteria. Sulfamethoxazole is a sulfonamide antibiotic that works by preventing the bacteria from producing essential components for growth. Trimethoprim is a dihydrofolate reductase inhibitor that blocks the production of folic acid, which is necessary for bacteria to multiply.

By targeting different steps in the bacterial growth process, the combination of these two medications provides a synergistic effect, making it more difficult for bacteria to survive and multiply, ultimately leading to the eradication of the infection.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, or stomach upset. These side effects are usually mild and go away on their own as your body adjusts to the medication.

However, some side effects may be more serious and require immediate medical attention. These can include severe allergic reactions, such as rash, itching, swelling, dizziness, or trouble breathing. If you experience any of these symptoms, seek medical help right away.

Drug Interactions

inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements, before starting treatment with Alphatram. Certain medications may interact with Sulfamethoxazole and Trimethoprim, potentially increasing the risk of side effects or reducing the effectiveness of the medications.

Common drug interactions may include anticoagulants, methotrexate, phenytoin, and certain diuretics. These are not exhaustive lists, so consult your healthcare provider or pharmacist for a complete list of potential drug interactions.

Precautions

Before taking Alphatram, inform your healthcare provider if you have any allergies, especially to sulfonamide antibiotics. Additionally, let your healthcare provider know if you have any medical conditions, such as kidney or liver disease, asthma, or a history of blood disorders.

Alphatram should be used with caution in pregnant or breastfeeding women, as the effects on the developing fetus or nursing infant are not fully known. Discuss the potential risks and benefits with your healthcare provider.

Storage

Patient Tips

• Take Alphatram exactly as prescribed, even if you start feeling better before completing the full course of treatment.
• If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
• Drink plenty of fluids while taking Alphatram to help prevent dehydration.
• Avoid prolonged exposure to sunlight or tanning beds while taking this medication, as it may increase your risk of sunburn.
• If you experience any unusual or persistent symptoms while taking Alphatram, such as worsening of your infection or new symptoms, contact your healthcare provider immediately.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

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• Sulfamethoxazole/Trimethoprim (Bactrim or Septra) and Pregnancy (Organization of Teratology Information Specialists) – PDF [Accessed 11 Jun. 2024] (online) Available at:
• Smith LG, Sensakovic J. Trimethoprim-sulfamethoxazole. Med Clin North Am. 1982 Jan;66(1):143-56. doi: 10.1016/s0025-7125(16)31448-1. [Accessed 28 Jun. 2024] Available at: