Alphovect 6mg/400mg Tablet

Introduction

Alphovect is a medication containing two active ingredients: Ivermectin and Albendazole. Ivermectin is an antiparasitic agent, while Albendazole is an anthelmintic (anti-worm) medication. This combination medication is primarily used for the treatment of certain parasitic infections, including strongyloidiasis, onchocerciasis (river blindness), and intestinal worm infections.

Uses

Alphovect is prescribed for the treatment of the following conditions:

• Strongyloidiasis: This is an intestinal infection caused by the parasitic worm Strongyloides stercoralis. Alphovect helps eliminate the worms and reduces the symptoms associated with the infection.
• Onchocerciasis (River Blindness): This is a parasitic infection caused by the worm Onchocerca volvulus, which is transmitted through the bites of infected blackflies. Alphovect helps kill the worms and alleviate the symptoms of the infection.
• Intestinal worm infections: Alphovect is also used for the treatment of various types of intestinal worm infections, including roundworm, whipworm, and hookworm infections.

Dosage and Administration

The dosage of Alphovect will depend on the specific condition being treated and the individual patient. Follow the instructions provided by your healthcare professional. Generally, the recommended dosage for adults and children above the age of 2 is a single tablet taken orally, with or without food. However. Consult your healthcare provider for the correct dosage based on your specific situation.

Mechanism of Action

Alphovect contains two active ingredients that work in different ways to combat parasitic infections. Ivermectin acts by paralyzing and killing the parasites, while Albendazole inhibits the uptake of glucose by the parasites, leading to their eventual death. Together, these medications help eliminate the parasites from the body, thereby treating the infections.

Side Effects

Common side effects may include nausea, vomiting, abdominal pain, diarrhea, dizziness, and headache. These side effects are usually mild and transient.

In rare cases, more serious side effects may occur. If you experience any of the following symptoms, seek immediate medical attention:

• Allergic reactions such as rash, itching, swelling, or difficulty breathing
• Severe stomach pain
• Persistent vomiting
• Vision problems or changes
• Neurological symptoms such as seizures or confusion

Drug Interactions

inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some medications may interact with Alphovect and affect its efficacy or increase the risk of side effects. Common drug interactions include:

• Anticonvulsant medications such as phenytoin or carbamazepine
• Anticoagulant medications such as warfarin
• Antacids containing aluminum or magnesium hydroxide
• Certain antibiotics such as erythromycin or clarithromycin

This is not an exhaustive list, and other drugs may also interact with Alphovect. Consult your healthcare provider for a comprehensive list of potential drug interactions.

Precautions

Before using Alphovect, inform your healthcare provider about any medical conditions you have and any medications you are taking. This medication may not be suitable for everyone, and certain precautions should be taken:

• Contraindications: Alphovect should not be used in individuals who are hypersensitive to Ivermectin, Albendazole, or any other components of the medication. It is also contraindicated during pregnancy and breastfeeding.
• Liver Dysfunction: Individuals with liver disease or impaired liver function should use Alphovect with caution and under the guidance of a healthcare professional.
• Children: Alphovect should not be used in children younger than 2 years old unless specifically prescribed by a healthcare professional.
• Other Medications: Inform your healthcare provider about all the medications you are taking, as some medications may interact with Alphovect.

Storage

Alphovect should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use the medication after the expiration date printed on the packaging.

Patient Tips

• Take the medication exactly as prescribed by your healthcare provider. Do not exceed the recommended dosage or use it for a longer duration than instructed.
• complete the full course of treatment, even if you start feeling better before the course is complete. This will ensure that the infection is fully treated.
• If you experience any concerning side effects or have any questions or concerns, do not hesitate to contact your healthcare provider.
• Remember to inform your healthcare provider about any other medications you are taking, including over-the-counter medications and herbal supplements.
• Store the medication in a cool, dry place and keep it out of reach of children and pets.
• Follow good hygiene practices, such as washing hands regularly, to prevent the spread of infection.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Mebendazole: a medicine to treat worms (NHS UK) [Accessed 6 Jun. 2024] (online) Available at:
• Ivermectin 3 mg, tablets (Health Professionals SmPC) Available at:
• Albendazole (Drugs.com) [Accessed 3 Jun. 2024] (online) Available at:
• albendazole (RX) [Accessed 15 Jun. 2024] (online) Available at:
• Albendazole (MedlinePlus) [Accessed 7 Jun. 2024] (online) Available at:
• Zhu L, Kuang X, Zhang G, Liang L, Liu D, Hu B, Xie Z, Li H, Liu H, Ye M, Chen X, Liu J. Albendazole induces immunotherapy response by facilitating ubiquitin-mediated PD-L1 degradation. J Immunother Cancer. 2022 May;10(5):e003819. doi: 10.1136/jitc-2021-003819. [Accessed 30 Jun. 2024] Available at: