Amedazol O Syrup

Introduction

Amedazol O is a prescription medication that contains two active ingredients: Ofloxacin and Metronidazole. It is commonly used to treat a variety of bacterial and protozoal infections.

Uses

Amedazol O is primarily prescribed for the treatment of the following conditions:

• Bacterial infections: It is effective against a wide range of bacterial infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, and gastrointestinal infections.
• Protozoal infections: It is also used to treat certain protozoal infections, such as amoebiasis, giardiasis, and trichomoniasis.

Dosage and Administration

The dosage of Amedazol O may vary depending on the specific infection being treated, the severity of the infection, and the patient’s age and overall health. Follow the instructions provided by your healthcare professional.

Generally, the recommended dosage for adults is 10 ml of the syrup, taken twice a day, or as directed by your doctor. For children, the dosage will be adjusted based on their weight and age.

Amedazol O should be taken with food to improve its absorption. Shake the bottle well before each use and use a measuring cup or spoon to ensure accurate dosage.

Mechanism of Action

Amedazol O contains two active ingredients: Ofloxacin and Metronidazole.

• Ofloxacin belongs to a class of antibiotics called fluoroquinolones. It works by inhibiting the bacterial DNA gyrase enzyme, preventing the replication and repair of bacterial DNA. This ultimately leads to the death of the bacteria.
• Metronidazole is an antibiotic and antiprotozoal medication. It works by interfering with the DNA synthesis of bacteria and protozoa, leading to their death.

Side Effects

Common side effects may include:

• Nausea and vomiting
• Diarrhea
• Abdominal pain
• Headache
• Dizziness
• Skin rash or itching

If any of these side effects persist or worsen, consult your healthcare professional.

Serious side effects are rare but can occur. If you experience any of the following symptoms, seek immediate medical attention:

• Severe diarrhea or bloody stools
• Signs of an allergic reaction (e.g., rash, itching, swelling, severe dizziness, difficulty breathing)

Drug Interactions

Amedazol O may interact with other medications or substances. Inform your healthcare professional about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements.

Common drug interactions with Amedazol O include:

• Warfarin: Amedazol O may increase the risk of bleeding when taken with warfarin or other blood thinners.
• Antacids: Taking antacids that contain aluminum or magnesium may decrease the absorption of Amedazol O. It is recommended to take the syrup at least 2 hours before or after taking antacids.

It is not an exhaustive list, and there may be other medications that can interact with Amedazol O. Always consult your healthcare professional for personalized advice.

Precautions

Before taking Amedazol O, consider the following precautions:

• Allergy: If you have a known allergy to Ofloxacin, Metronidazole, or any other fluoroquinolones or nitroimidazole medications, you should avoid taking Amedazol O.
• Pregnancy and breastfeeding: Amedazol O should be used with caution during pregnancy and breastfeeding. Discuss the potential risks and benefits with your healthcare professional.
• Liver or kidney disease: Amedazol O may require dose adjustments in patients with liver or kidney disease. Your healthcare professional will determine the appropriate dosage for you.
• Alcohol: It is advisable to avoid consuming alcohol while taking Amedazol O, as it may increase the risk of side effects such as dizziness and nausea.

Storage

Amedazol O should be stored at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed when not in use. Do not freeze the medication. Keep all medications out of the reach of children.

Patient Tips

Here are some additional tips for patients using Amedazol O:

• Take the medication exactly as prescribed by your healthcare professional. Do not exceed the recommended dosage or stop taking the medication without consulting your doctor.
• Complete the full course of treatment, even if you start feeling better before it is finished. This will help ensure that the infection is completely cleared.
• If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• If you experience any unusual symptoms or side effects while taking Amedazol O, consult your healthcare professional promptly.
• Maintain good hygiene practices, such as regular handwashing, to prevent the spread of infections.
• If you are unsure about any aspect of your treatment or have any questions, do not hesitate to reach out to your healthcare professional for clarification.
• Store the medication in a safe place, away from children and pets, to prevent accidental ingestion.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Metronidazole: antibiotic to treat infections (NHS UK) [Accessed 6 Jun. 2024] (online) Available at:
• Acea 0.75% w/w Gel (Health Professionals SmPC) Available at:
• Metronidazole (Drugs.com) [Accessed 26 Jun. 2024] (online) Available at:
• metronidazole (RX) [Accessed 5 Jun. 2024] (online) Available at:
• Metronidazole Injection (MedlinePlus) [Accessed 5 Jun. 2024] (online) Available at:
• Dingsdag SA, Hunter N. Metronidazole: an update on metabolism, structure-cytotoxicity and resistance mechanisms. J Antimicrob Chemother. 2018 Feb 1;73(2):265-279. doi: 10.1093/jac/dkx351. [Accessed 12 Jun. 2024] Available at: