Amlozaar Tablet

Introduction

Amlozaar is a prescription medication that combines two active ingredients: Losartan and Amlodipine. It is commonly used to treat high blood pressure (hypertension) and to reduce the risk of stroke in patients with an enlarged heart (left ventricular hypertrophy).

Uses

Amlozaar is primarily prescribed for the following conditions:

• Hypertension (high blood pressure): It helps to lower blood pressure, reducing the risk of heart attacks, strokes, and kidney problems.
• Left ventricular hypertrophy: It is used to reduce the risk of stroke in patients with an enlarged heart.

Dosage and Administration

• The dosage of Amlozaar may vary depending on the individual’s condition and medical history. Follow your healthcare provider’s instructions.
• The tablets are typically taken orally with or without food.
• The usual starting dose for most patients is one tablet per day, but your healthcare provider may adjust the dose based on your response to treatment.
• take the medication regularly and at the same time each day to get the maximum benefit.

Mechanism of Action

Amlozaar contains two active ingredients: Losartan and Amlodipine. These medications work in different ways to help lower blood pressure and reduce the risk of stroke.

• Losartan belongs to a class of medications called angiotensin II receptor blockers (ARBs). It works by blocking the action of a hormone called angiotensin II, which causes blood vessels to narrow. By blocking the effects of angiotensin II, Losartan helps relax and widen the blood vessels, reducing blood pressure.
• Amlodipine belongs to a class of medications called calcium channel blockers. It works by relaxing the blood vessels and reducing the workload on the heart, making it easier for the heart to pump blood.

Together, Losartan and Amlodipine work synergistically to lower blood pressure and reduce the risk of stroke.

Side Effects

Amlozaar may cause side effects in some individuals. Common side effects may include:

• Dizziness or lightheadedness
• Fatigue or tiredness
• Swelling in the ankles or feet
• Flushing (redness of the face)

If any of these side effects persist or worsen, consult your healthcare provider.

Serious side effects are rare but may include:

• Allergic reactions, such as difficulty breathing, rash, or itching
• Rapid or irregular heartbeat
• Severe dizziness or fainting
• Swelling of the face, lips, tongue, or throat

If you experience any serious side effects, seek immediate medical attention.

Drug Interactions

Amlozaar may interact with certain medications, including:

• Other blood pressure medications: Combining Amlozaar with other medications that lower blood pressure may result in an excessive drop in blood pressure.
• Potassium supplements or salt substitutes containing potassium: These may increase the levels of potassium in the blood, which can be dangerous.
• Nonsteroidal anti-inflammatory drugs (NSAIDs): These medications may reduce the effectiveness of Amlozaar.

Inform your healthcare provider about all the medications you are taking, including over-the-counter medications, herbal supplements, and vitamins, to avoid potential drug interactions.

Precautions

Before taking Amlozaar, consider the following precautions:

• Inform your healthcare provider about any allergies you have, especially to Losartan, Amlodipine, or any other medications.
• Inform your healthcare provider about any medical conditions you have, including liver disease, kidney disease, heart disease, or diabetes.
• Amlozaar is generally not recommended during pregnancy or while breastfeeding. Consult your healthcare provider for guidance.

Storage

Amlozaar should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of the reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Take Amlozaar exactly as prescribed by your healthcare provider. Do not change the dosage or stop taking the medication without consulting your healthcare provider.
• It may take several weeks for the full effects of the medication to be seen. Continue taking the medication regularly even if you feel well.
• Avoid consuming grapefruit or grapefruit juice while taking Amlozaar, as it may interact with the medication.
• If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Follow a healthy lifestyle, including regular exercise, a balanced diet, and limiting alcohol consumption, to complement the effects of Amlozaar in managing your blood pressure.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Amlodipine: a medicine to treat high blood pressure (NHS UK) [Accessed 24 Jun. 2024] (online) Available at:
• Amlodipine / Valsartan 10 mg / 160 mg film-coated tablets (Health Professionals SmPC) Available at:
• Amlodipine (Drugs.com) [Accessed 13 Jun. 2024] (online) Available at:
• amlodipine (RX) [Accessed 22 Jun. 2024] (online) Available at:
• Amlodipine (MedlinePlus) [Accessed 24 Jun. 2024] (online) Available at:
• van Zwieten PA. Amlodipine: an overview of its pharmacodynamic and pharmacokinetic properties. Clin Cardiol. 1994 Sep;17(9 Suppl 3):III3-6. [Accessed 6 Jun. 2024] Available at: