Amne-Tad 20mg Orally Disintegrating Strip

Introduction

Amne-Tad is an orally disintegrating strip medication that contains the active ingredient Tadalafil. It is available under the brand name Amne-Tad. Tadalafil is a medication commonly used for the treatment of erectile dysfunction (ED) and benign prostatic hyperplasia (BPH). It belongs to a class of medications known as phosphodiesterase type 5 (PDE5) inhibitors, which work by increasing blood flow to the penis, helping to achieve and maintain an erection.

Uses

Amne-Tad is primarily prescribed for two main conditions:

• Erectile Dysfunction (ED): Amne-Tad is used to treat men with difficulty achieving or maintaining an erection during sexual activity. It helps to increase blood flow to the penis, resulting in improved erectile function.
• Benign Prostatic Hyperplasia (BPH): Amne-Tad is also used in the treatment of BPH, a condition that causes the prostate gland to enlarge, leading to urinary problems. By relaxing the muscles in the prostate and bladder, Amne-Tad helps to improve urinary symptoms associated with BPH, such as frequent urination, urgency, and weak urine flow.

Dosage and Administration

The recommended dosage of Amne-Tad will vary depending on the individual and the condition being treated. Follow the instructions provided by your healthcare professional or the information on the product label.

• For Erectile Dysfunction: The typical starting dose is 10 mg taken orally before sexual activity, with or without food. The dose may be adjusted based on individual response and tolerability, up to a maximum of 20 mg per day.
• For Benign Prostatic Hyperplasia: The recommended starting dose is 5 mg taken once a day, at approximately the same time each day. The dose may be adjusted based on individual response and tolerability, up to a maximum of 5 mg per day.

Amne-Tad is an orally disintegrating strip that dissolves quickly on the tongue without the need for water. Follow the specific instructions provided with the medication for proper administration.

Mechanism of Action

Amne-Tad contains Tadalafil, which works by inhibiting the action of an enzyme called phosphodiesterase type 5 (PDE5). This enzyme is responsible for breaking down a substance called cyclic guanosine monophosphate (cGMP) in the body. By inhibiting PDE5, Tadalafil helps to increase the levels of cGMP, which relaxes the smooth muscles and increases blood flow to the penis, resulting in improved erectile function. It also relaxes the muscles in the prostate and bladder, improving urinary symptoms associated with BPH.

Side Effects

Common side effects may include:

• Headache
• Upset stomach
• Flushing (redness or warmth in the face, neck, or chest)
• Nasal congestion
• Back pain
• Muscle aches
• Diarrhea

note that these side effects are usually mild and temporary. However, if these side effects persist or worsen, it is advisable to consult your healthcare professional.

In rare cases, Amne-Tad may cause more serious side effects, including sudden vision loss, hearing loss, chest pain, and priapism (a painful erection lasting longer than 4 hours). If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Amne-Tad may interact with certain medications, potentially leading to adverse effects or reducing the effectiveness of either medication. Inform your healthcare professional about all the medications you are currently taking, including prescription and over-the-counter medications, as well as any herbal supplements or vitamins.

Some common medications that may interact with Amne-Tad include:

• Nitrates: Taking Amne-Tad with nitrates, such as nitroglycerin, can cause a sudden and severe drop in blood pressure. This combination should be avoided.
• Alpha-blockers: Combining Amne-Tad with alpha-blockers, used to treat high blood pressure or prostate problems, may also cause a sudden drop in blood pressure. Your healthcare professional may need to adjust the dosages of these medications.
• Other PDE5 inhibitors: Taking Amne-Tad with other medications in the same class, such as sildenafil or vardenafil, may increase the risk of side effects and should be avoided.

This is not an exhaustive list of potential drug interactions. Always consult your healthcare professional for personalized advice based on your specific medication regimen.

Precautions

Before using Amne-Tad, consider certain precautions to ensure its safe and effective use:

• Contraindications: Amne-Tad is contraindicated in individuals with a known hypersensitivity to Tadalafil or any other component of the medication. It should not be used in combination with nitrates or nitric oxide donors.
• Cardiovascular Conditions: Amne-Tad should be used with caution in individuals with a history of cardiovascular disease, including heart attack, stroke, or arrhythmias. It is advisable to consult a healthcare professional before starting Amne-Tad.
• Liver and Kidney Function: Individuals with impaired liver or kidney function may require dose adjustments or closer monitoring when taking Amne-Tad. Inform your healthcare professional about any pre-existing liver or kidney conditions.
• Grapefruit Juice: Consuming grapefruit juice while taking Amne-Tad may increase the levels of Tadalafil in the body, potentially increasing the risk of side effects. It is advisable to avoid grapefruit juice during Amne-Tad treatment.
• Alcohol: Drinking alcohol in excess while taking Amne-Tad may increase the risk of dizziness, lightheadedness, and low blood pressure. It is advisable to limit alcohol consumption.

Storage

Amne-Tad should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not use Amne-Tad beyond the expiration date printed on the packaging.

Patient Tips

• Follow the instructions provided by your healthcare professional or the information on the product label regarding the dosage and administration of Amne-Tad.
• Take Amne-Tad as needed for the treatment of erectile dysfunction or as prescribed for the treatment of benign prostatic hyperplasia. Do not exceed the recommended dose.
• If you experience any new or worsening symptoms while taking Amne-Tad, such as chest pain, vision or hearing changes, or prolonged erection, seek immediate medical attention.
• Inform your healthcare professional about all the medications you are currently taking, including prescription and over-the-counter medications, as well as any herbal supplements or vitamins.
• If you have any questions or concerns about Amne-Tad, do not hesitate to consult your healthcare professional for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Idiopathic pulmonary fibrosis (NHS UK) [Accessed 17 Jun. 2024] (online) Available at:
• Adcirca (Health Professionals SmPC) Available at:
• Tadalafil (Drugs.com) [Accessed 20 Jun. 2024] (online) Available at:
• tadalafil (RX) [Accessed 22 Jun. 2024] (online) Available at:
• Tadalafil (MedlinePlus) [Accessed 19 Jun. 2024] (online) Available at:
• Kaku Y, Chiba K, Sato K, Onishi A, Ishida T, Okada K, Fujisawa M. Protective effects of tadalafil against cisplatin-induced spermatogenic dysfunction. Biochem Biophys Res Commun. 2022 May 7;603:123-129. doi: 10.1016/j.bbrc.2022.02.113. Epub 2022 Mar 6. [Accessed 4 Jun. 2024] Available at: