Appkit 125mg/80mg Capsule

Introduction

Appkit is a prescription medication that contains the active ingredient Aprepitant. It is used to treat nausea and vomiting caused by chemotherapy or certain types of surgery.

Uses

Appkit is prescribed to prevent nausea and vomiting in individuals undergoing chemotherapy for cancer treatment. It is also used to prevent nausea and vomiting after undergoing certain types of surgery, such as abdominal surgery or surgery to remove the uterus.

Dosage and Administration

The dosage of Appkit may vary depending on the specific chemotherapy regimen or type of surgery. Follow the instructions provided by your healthcare professional. Generally, the recommended dose for adults is one capsule taken orally, one hour before chemotherapy or surgery. It can be taken with or without food.

Mechanism of Action

Aprepitant, the active ingredient in Appkit, works by blocking the action of a substance called substance P in the brain. Substance P is involved in the transmission of signals that trigger nausea and vomiting. By blocking substance P, Aprepitant helps to prevent and reduce chemotherapy-induced and post-operative nausea and vomiting.

Side Effects

Common side effects may include fatigue, constipation, diarrhea, and loss of appetite. These side effects are usually mild and go away on their own. However, if they persist or become bothersome, consult your healthcare professional.

In rare cases, Appkit may cause more serious side effects. These can include allergic reactions, such as rash, itching, or swelling of the face, lips, or tongue. Seek immediate medical attention if you experience any severe or unusual symptoms while taking this medication.

Drug Interactions

Appkit may interact with certain medications, including but not limited to:

• Warfarin: Aprepitant may increase the blood-thinning effects of warfarin, which can increase the risk of bleeding. Close monitoring of blood clotting levels is advised.
• Cyclosporine: Aprepitant may decrease the effectiveness of cyclosporine, a medication used to prevent organ rejection after transplantation. Dosage adjustments may be necessary.
• Dexamethasone: Aprepitant may increase the blood levels of dexamethasone, a corticosteroid medication. Close monitoring of dexamethasone levels and potential dosage adjustments may be needed.

Inform your healthcare professional about all medications you are taking, including prescription, over-the-counter, and herbal products, before starting Appkit.

Precautions

Before taking Appkit, inform your healthcare professional if you have any allergies, medical conditions, or if you are pregnant or breastfeeding. This medication may not be suitable for everyone, and your healthcare professional can determine whether it is safe and appropriate for you.

Appkit should not be used in combination with certain medications, such as pimozide or terfenadine, as this may cause serious interactions. Additionally, avoid consuming grapefruit or grapefruit juice while taking Appkit, as it may increase the levels of Aprepitant in your body.

Storage

Appkit should be stored at room temperature, away from heat, moisture, and light. Keep the medication out of reach of children and pets. Do not use Appkit if it has passed the expiration date printed on the packaging.

Patient Tips

• Take Appkit exactly as prescribed by your healthcare professional.
• If you forget to take a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• If you experience any unusual or severe side effects while taking Appkit, contact your healthcare professional immediately.
• Follow any additional instructions provided by your healthcare professional, such as dietary restrictions or other medications to take along with Appkit.
• Keep track of your symptoms and report any changes to your healthcare professional during your treatment with Appkit.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Aprepitant 125 mg hard capsules (Health Professionals SmPC) Available at:
• Aprepitant (Drugs.com) [Accessed 0 Jun. 2024] (online) Available at:
• aprepitant (RX) [Accessed 26 Jun. 2024] (online) Available at:
• Aprepitant (MedlinePlus) [Accessed 17 Jun. 2024] (online) Available at:
• Vazirian F, Samadi S, Rahimi H, Sadeghi M, Mohammadpour AH. Aprepitant, fosaprepitant and risk of ifosfamide-induced neurotoxicity: a systematic review. Cancer Chemother Pharmacol. 2022 Jul;90(1):1-6. doi: 10.1007/s00280-022-04439-x. Epub 2022 May 30. [Accessed 4 Jun. 2024] Available at: