Introduction
Apraize is a prescription medication that contains the active ingredient Apremilast. It is available under the brand name Apraize. This medication is primarily used to treat certain inflammatory conditions, including psoriasis and psoriatic arthritis.
Uses
Apraize is prescribed to manage the symptoms of psoriasis and psoriatic arthritis. Psoriasis is a chronic skin condition characterized by red, scaly patches on the skin, while psoriatic arthritis is a type of arthritis that affects some individuals with psoriasis. This medication helps reduce inflammation in the body, which can alleviate the symptoms associated with these conditions.
Dosage and Administration
follow your healthcare provider’s instructions when taking Apraize. The dosage may vary depending on your specific condition and medical history. Typically, the recommended starting dose is 10 mg twice daily. Your healthcare provider may adjust the dosage based on your response to the medication.
Apraize should be taken orally with or without food. Swallow the tablet whole with a glass of water, without crushing or chewing it. If you have difficulty swallowing the tablet, talk to your healthcare provider for alternative administration options.
Mechanism of Action
The active ingredient in Apraize, Apremilast, works by inhibiting an enzyme called phosphodiesterase 4 (PDE4). By inhibiting PDE4, Apremilast helps reduce the production of certain inflammatory mediators in the body. This helps to decrease inflammation and alleviate the symptoms associated with psoriasis and psoriatic arthritis.
Side Effects
Common side effects may include diarrhea, nausea, headache, and upper respiratory tract infections. These side effects are usually mild and temporary. If any of these side effects persist or worsen, consult your healthcare provider.
In rare cases, Apraize may cause more serious side effects, such as depression or suicidal thoughts, weight loss, or allergic reactions. If you experience any of these serious side effects, seek immediate medical attention.
Drug Interactions
Apraize may interact with certain medications, including strong cytochrome P450 enzyme inducers (such as rifampin) and strong cytochrome P450 enzyme inhibitors (such as ketoconazole). Inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, and herbal products, to avoid potential drug interactions.
Precautions
Before taking Apraize, discuss any medical conditions or allergies you have with your healthcare provider. Inform them if you have a history of depression or suicidal thoughts, as this medication may increase the risk of these conditions.
Apraize is not recommended for use during pregnancy or breastfeeding, as its safety during these periods has not been established. If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider for alternative treatment options.
Storage
Patient Tips
- Follow your healthcare provider’s instructions regarding the dosage and administration of Apraize.
- If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- Do not double the dose to make up for a missed dose.
- It may take some time for Apraize to show its full effect. Be patient and continue taking the medication as prescribed.
- If you have any concerns or questions about Apraize, do not hesitate to consult your healthcare provider. They can provide you with personalized advice and guidance based on your specific condition.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Otezla 10 mg Film-coated Tablets (Health Professionals SmPC) Available at:
- Apremilast (Drugs.com) [Accessed 13 Jun. 2024] (online) Available at:
- apremilast tablet (RX) [Accessed 15 Jun. 2024] (online) Available at:
- Psoriatic arthritis (MedlinePlus) [Accessed 14 Jun. 2024] (online) Available at:
- Nassim D, Alajmi A, Jfri A, Pehr K. Apremilast in dermatology: A review of literature. Dermatol Ther. 2020 Nov;33(6):e14261. doi: 10.1111/dth.14261. Epub 2020 Sep 27. [Accessed 23 Jun. 2024] Available at:
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