Aptazone S 1000mg/500mg Injection

Introduction

Aptazone S is a prescription medication that contains two active ingredients: Cefoperazone and Sulbactam. Cefoperazone is a broad-spectrum antibiotic, while Sulbactam is a beta-lactamase inhibitor. This combination medication is commonly used to treat bacterial infections caused by susceptible organisms.

Uses

Aptazone S is indicated for the treatment of various infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, intra-abdominal infections, and gynecological infections. Note that this medication should be used only for infections caused by bacteria susceptible to Cefoperazone and Sulbactam.

Dosage and Administration

Aptazone S should be administered by a healthcare professional. The dosage and duration of treatment will depend on the specific infection being treated, as well as the patient’s age, weight, and overall health. Follow the instructions provided by your healthcare provider.

Mechanism of Action

Cefoperazone, one of the active ingredients in Aptazone S, works by inhibiting the synthesis of bacterial cell walls, leading to the death of susceptible bacteria. Sulbactam, the other active ingredient, enhances the activity of Cefoperazone by inhibiting certain enzymes that can inactivate the antibiotic. Together, these two ingredients work synergistically to combat bacterial infections.

Side Effects

Common side effects may include pain or inflammation at the injection site, nausea, vomiting, diarrhea, and rash. These side effects are usually mild and transient. However, if any side effects persist or worsen, contact your healthcare provider.

Serious side effects are rare but may include severe allergic reactions, such as difficulty breathing, swelling of the face or throat, and rash. If you experience any of these symptoms, seek immediate medical attention.

Drug Interactions

Aptazone S may interact with certain medications, including other antibiotics, anticoagulants, and probenecid. Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. They can assess potential interactions and adjust your treatment accordingly.

Precautions

Before using Aptazone S, inform your healthcare provider about any known allergies to Cefoperazone, Sulbactam, or any other medications. Additionally, provide a comprehensive medical history, including any history of kidney or liver disease, as well as any ongoing medical conditions.

Note that Aptazone S should not be used in patients with a known hypersensitivity to Cephalosporin antibiotics or Beta-lactamase inhibitors. It is also contraindicated in patients with a history of severe allergic reactions to penicillin or other beta-lactam antibiotics.

Storage

Aptazone S should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of the reach of children and pets. Do not use the medication if the packaging is damaged or if the expiry date has passed. Follow any additional storage instructions provided by your healthcare provider or pharmacist.

Patient Tips

• Follow the prescribed dosage and duration of treatment as instructed by your healthcare provider.
• If you miss a dose, contact your healthcare provider for further instructions. Do not double the dose to make up for a missed one.
• Inform your healthcare provider about any side effects you experience during treatment.
• Do not use Aptazone S for viral infections, such as the common cold or flu, as it is only effective against bacterial infections.
• Complete the full course of treatment, even if you start to feel better before the prescribed duration is over.
• If you have any questions or concerns about Aptazone S, don’t hesitate to contact your healthcare provider or pharmacist for clarification.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Cefoperazone (Drugs.com) [Accessed 18 Jun. 2024] (online) Available at:
• ampicillin-sulbactam solution, reconstituted (recon soln) (RX) [Accessed 18 Jun. 2024] (online) Available at:
• LactMed: Drugs and Lactation Database (National Library of Medicine) [Accessed 17 Jun. 2024] (online) Available at:
• Wang Z, Li Z, Luo S, Yang Z, Xing Y, Pu C, Dong J. Cefoperazone and sulbactam-related eosinophilic peritonitis: a case report and literature review. J Int Med Res. 2021 Jun;49(6):3000605211025367. doi: 10.1177/03000605211025367. [Accessed 3 Jun. 2024] Available at: