Asponet 70 Injection

Introduction

Asponet is a prescription medication that contains the active ingredient Caspofungin. It is available in the form of an injection and is used to treat certain fungal infections.

Uses

Asponet is primarily prescribed to treat invasive candidiasis, a type of fungal infection caused by Candida species. It is also used to treat esophageal candidiasis, a fungal infection that affects the esophagus.

Dosage and Administration

Asponet is administered by healthcare professionals through a vein (intravenous route). The dosage and duration of treatment may vary depending on the specific infection being treated and the patient’s individual response. Follow the instructions provided by your healthcare provider.

Mechanism of Action

Caspofungin, the active ingredient in Asponet, belongs to a class of medications called echinocandins. It works by inhibiting the synthesis of a component called beta-(1,3)-D-glucan in the cell wall of the fungus. This weakens and damages the fungal cell wall, ultimately leading to the death of the fungus.

Side Effects

Common side effects may include fever, headache, nausea, vomiting, diarrhea, and abdominal pain. These side effects are usually mild and temporary.

Serious side effects are rare but can occur. If you experience any of the following, seek immediate medical attention: severe allergic reactions (such as rash, itching, swelling, dizziness, or difficulty breathing), liver problems (such as yellowing of the skin or eyes, dark urine, or persistent nausea), or severe skin reactions (such as blistering or peeling of the skin).

Drug Interactions

Asponet may interact with other medications, so inform your healthcare provider about all the medications you are currently taking. Some medications that may interact with Asponet include cyclosporine, rifampin, and warfarin. These interactions can affect the effectiveness or increase the risk of side effects of either medication. Your healthcare provider will monitor you closely if you are taking these medications together.

Precautions

Before using Asponet, inform your healthcare provider about any allergies you have, especially if you are allergic to caspofungin or any other antifungal medications. Disclose your medical history, especially if you have liver disease or any other medical conditions.

Asponet should be used with caution in pregnant and breastfeeding women. Discuss the potential risks and benefits with your healthcare provider.

Storage

Asponet should be stored in a refrigerator between 2°C and 8°C (36°F and 46°F). Protect the medication from light and do not freeze it. Keep it out of the reach of children.

Patient Tips

• Follow the dosage instructions provided by your healthcare provider and complete the full course of treatment, even if you start feeling better.
• Report any new or worsening symptoms to your healthcare provider.
• If you miss a dose, contact your healthcare provider for further instructions.
• Keep all follow-up appointments with your healthcare provider to monitor your progress and response to treatment.
• If you have any concerns or questions about your medication, don’t hesitate to reach out to your healthcare provider for clarification.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• CANCIDAS 50 mg (formerly Caspofungin MSD) powder for concentrate for solution for infusion (Health Professionals SmPC) Available at:
• Caspofungin (Drugs.com) [Accessed 0 Jun. 2024] (online) Available at:
• caspofungin solution, reconstituted (recon soln) (RX) [Accessed 8 Jun. 2024] (online) Available at:
• Caspofungin Injection (MedlinePlus) [Accessed 24 Jun. 2024] (online) Available at:
• Thompson GR 3rd, Soriano A, Cornely OA, Kullberg BJ, Kollef M, Vazquez J, Honore PM, Bassetti M, Pullman J, Chayakulkeeree M, Poromanski I, Dignani C, Das AF, Sandison T, Pappas PG; ReSTORE trial investigators. Rezafungin versus caspofungin for treatment of candidaemia and invasive candidiasis (ReSTORE): a multicentre, double-blind, double-dummy, randomised phase 3 trial. Lancet. 2023 Jan 7;401(10370):49-59. doi: 10.1016/S0140-6736(22)02324-8. Epub 2022 Nov 25. [Accessed 25 Jun. 2024] Available at: