Asthagrip DM Tablet

Introduction

Asthagrip DM is a prescription medication that contains three active ingredients: Acebrophylline, Desloratadine, and Montelukast. It is used to treat respiratory conditions such as asthma, chronic obstructive pulmonary disease (COPD), and allergic rhinitis. Asthagrip DM is available under various brand names and is commonly prescribed to provide relief from symptoms like coughing, wheezing, shortness of breath, and nasal congestion.

Uses

Asthagrip DM is primarily prescribed for the following conditions:

• Asthma: Asthagrip DM helps in relieving the symptoms of asthma, such as wheezing, coughing, and difficulty breathing. It may be used as a maintenance therapy to control asthma symptoms and prevent exacerbations.
• Chronic Obstructive Pulmonary Disease (COPD): This medication can also be prescribed to manage symptoms of COPD, including wheezing, coughing, and shortness of breath. It may help improve lung function and reduce exacerbations.
• Allergic Rhinitis: Asthagrip DM is effective in providing relief from symptoms associated with allergic rhinitis, such as sneezing, nasal congestion, and itching. It helps in reducing inflammation in the nasal passages and alleviating discomfort.

Dosage and Administration

follow the dosage instructions provided by your healthcare professional. The recommended dosage of Asthagrip DM may vary depending on the severity of your condition and your individual response to the medication. Typically, the usual adult dose is one tablet taken orally once daily. It is advisable to take the tablet with a glass of water, with or without food. Do not crush or chew the tablet; swallow it whole.

Mechanism of Action

Asthagrip DM contains three active ingredients that work in different ways to provide relief from respiratory symptoms:

• Acebrophylline: It acts as a bronchodilator and mucolytic agent, helping to widen the airways and reduce the viscosity of mucus, making it easier to cough up.
• Desloratadine: It is an antihistamine that blocks the action of histamine, a chemical released during an allergic reaction. By inhibiting histamine, Desloratadine helps in reducing nasal congestion, sneezing, and itching.
• Montelukast: It is a leukotriene receptor antagonist that helps in reducing inflammation and constriction of the airways. By blocking the effects of leukotrienes, Montelukast helps in relieving asthma and allergy symptoms.

Side Effects

Common side effects may include headache, nausea, dry mouth, and dizziness. These side effects are usually mild and temporary. However, if you experience any persistent or severe side effects, consult your healthcare professional.

In rare cases, Asthagrip DM may cause serious side effects such as allergic reactions, difficulty breathing, chest pain, or irregular heartbeat. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Asthagrip DM may interact with other medications and substances, which can affect its effectiveness or increase the risk of side effects. Inform your healthcare professional about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some common drug interactions to be aware of include:

• Theophylline: Asthagrip DM may increase the blood levels of theophylline, leading to an increased risk of side effects. Your healthcare professional may need to adjust the dosage of theophylline if you are taking it along with Asthagrip DM.
• Anticoagulants: Montelukast, one of the active ingredients in Asthagrip DM, may interact with certain anticoagulant medications, increasing the risk of bleeding. Regular monitoring of your blood clotting parameters may be necessary if you are taking anticoagulants.

This is not an exhaustive list of drug interactions. Always consult your healthcare professional for specific guidance based on your individual circumstances.

Precautions

Before taking Asthagrip DM, consider certain precautions to ensure its safe and effective use:

• Allergy: If you have a known allergy to any of the active ingredients in Asthagrip DM or similar medications, inform your healthcare professional. Allergic reactions may include rash, itching, swelling, or difficulty breathing.
• Pregnancy and Breastfeeding: Asthagrip DM should be used with caution during pregnancy and breastfeeding. Discuss the potential risks and benefits with your healthcare professional before using this medication.
• Liver or Kidney Impairment: If you have liver or kidney impairment, your healthcare professional may need to adjust the dosage of Asthagrip DM. Provide your complete medical history to your healthcare professional.
• Other Medications: Inform your healthcare professional about all the medications you are taking to avoid potential drug interactions.

Storage

Asthagrip DM should be stored in a cool and dry place, away from direct sunlight and moisture. Keep it out of the reach of children and pets. Do not use the medication after the expiration date mentioned on the packaging. If you have any expired or unused medication, consult your healthcare professional or pharmacist for proper disposal methods.

Patient Tips

• Take the medication exactly as prescribed by your healthcare professional. Do not exceed the recommended dosage.
• If you forget to take a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not stop taking Asthagrip DM abruptly without consulting your healthcare professional, as it may lead to a worsening of your symptoms.
• If you experience any new or worsening symptoms while taking Asthagrip DM, such as increased wheezing or difficulty breathing, contact your healthcare professional.
• Follow a healthy lifestyle, including regular exercise, a balanced diet, and avoiding triggers that may worsen your respiratory symptoms.
• Attend regular check-ups with your healthcare professional to monitor your response to the medication and make any necessary adjustments to your treatment plan.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Montelukast: a medicine to prevent asthma symptoms (NHS UK) [Accessed 10 Jun. 2024] (online) Available at:
• Desloratadine 5 mg film-coated tablets (Health Professionals SmPC) Available at:
• Kola Nut Uses, Benefits & Dosage Herbal Database (Drugs.com) [Accessed 28 Jun. 2024] (online) Available at:
• desloratadine (RX) [Accessed 14 Jun. 2024] (online) Available at:
• Desloratadine (MedlinePlus) [Accessed 24 Jun. 2024] (online) Available at:
• Kuriachan S, Amberkar MB, Mohan MK, Shahul HA, Kishore MK. Acebrophylline-induced angioedema. Indian J Pharmacol. 2015 Mar-Apr;47(2):219-20. doi: 10.4103/0253-7613.153435. [Accessed 14 Jun. 2024] Available at: