Introduction
AZ Mide is a prescription medication that contains the active ingredient Acetazolamide. It is available under the brand name AZ Mide. This medication is primarily used to treat certain types of glaucoma, a condition characterized by increased pressure within the eye. Acetazolamide is a carbonic anhydrase inhibitor that helps reduce intraocular pressure and relieve symptoms associated with glaucoma.
Uses
AZ Mide is prescribed for the treatment of glaucoma, including open-angle glaucoma, secondary glaucoma, and preoperatively in acute angle-closure glaucoma. It can also be used to manage certain symptoms of altitude sickness, such as headache and dizziness.
Dosage and Administration
The dosage of AZ Mide may vary depending on the individual’s condition and response to treatment. Follow the instructions provided by your healthcare professional. Generally, the recommended dose for glaucoma is 250 to 1000 mg per day, divided into two to four doses. For altitude sickness, the usual dose is 500 mg per day, starting one to two days before ascent and continuing for two to three days after reaching the desired altitude.
AZ Mide should be taken orally with a full glass of water. It can be taken with or without food. Avoid crushing or chewing the tablets; swallow them whole.
Mechanism of Action
Acetazolamide, the active ingredient in AZ Mide, works by inhibiting the enzyme carbonic anhydrase. This enzyme is involved in the production of bicarbonate, which is necessary for the formation of aqueous humor in the eye. By inhibiting carbonic anhydrase, acetazolamide reduces the production of aqueous humor, thereby decreasing intraocular pressure and relieving symptoms of glaucoma.
Side Effects
Common side effects may include frequent urination, drowsiness, loss of appetite, and taste alterations. These side effects are usually mild and temporary. However, if they persist or become bothersome, consult your healthcare professional.
Serious side effects are rare but can occur. These may include severe allergic reactions, such as rash, itching, swelling, dizziness, or difficulty breathing. If you experience any of these serious side effects, seek immediate medical attention.
Drug Interactions
AZ Mide may interact with certain medications, including other carbonic anhydrase inhibitors, anticoagulants, salicylates, and certain anticonvulsants. These interactions can affect the effectiveness or increase the risk of side effects of either medication. Inform your healthcare professional about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements.
Precautions
Before taking AZ Mide, inform your healthcare professional about any known allergies, medical conditions, or medications you are currently taking. This medication should be used with caution in patients with a history of kidney or liver disease, respiratory disorders, or electrolyte imbalances.
AZ Mide is contraindicated in patients with a known hypersensitivity to acetazolamide or sulfonamides. It should not be used in patients with severe kidney or liver dysfunction, chronic non-congestive angle-closure glaucoma, or certain metabolic disorders.
Storage
AZ Mide should be stored at room temperature, away from direct sunlight and moisture. Keep it out of the reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.
Patient Tips
- Take AZ Mide exactly as prescribed by your healthcare professional.
- Do not stop taking the medication without consulting your doctor, even if you start feeling better.
- Keep a regular schedule for taking the medication to ensure its effectiveness.
- If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- attend regular follow-up appointments with your healthcare professional to monitor your response to the medication and assess any potential side effects.
- If you experience any unusual or severe side effects, contact your healthcare professional immediately.
- Inform your healthcare professional about any other medications you are taking, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Acetazolamide 250mg Tablets (Health Professionals SmPC) Available at:
- Acetazolamide (Drugs.com) [Accessed 18 Jun. 2024] (online) Available at:
- acetazolamide (RX) [Accessed 22 Jun. 2024] (online) Available at:
- Acetazolamide (MedlinePlus) [Accessed 30 Jun. 2024] (online) Available at:
- Meekers E, Dauw J, Martens P, Dhont S, Verbrugge FH, Nijst P, Ter Maaten JM, Damman K, Mebazaa A, Filippatos G, Ruschitzka F, Tang WHW, Dupont M, Mullens W. Renal function and decongestion with acetazolamide in acute decompensated heart failure: the ADVOR trial. Eur Heart J. 2023 Oct 1;44(37):3672-3682. doi: 10.1093/eurheartj/ehad557. [Accessed 11 Jun. 2024] Available at:
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