Basugine 100IU/ml Injection

Introduction

Basugine is a prescription medication that contains the active ingredient Insulin Glargine. It is commonly used to help manage blood sugar levels in patients with diabetes. Insulin Glargine is a long-acting insulin analog that helps regulate glucose metabolism in the body.

Uses

Basugine is primarily prescribed for the treatment of diabetes mellitus, a chronic condition characterized by high blood sugar levels. It is commonly used in patients with type 1 diabetes, where the body does not produce enough insulin, as well as in patients with type 2 diabetes, where the body does not effectively use insulin. By providing a steady supply of insulin, Basugine helps control blood sugar levels and prevent complications associated with diabetes.

Dosage and Administration

Basugine should be administered subcutaneously (under the skin) once daily. The dosage and administration instructions may vary depending on individual patient factors such as age, weight, and blood sugar levels. Follow the instructions provided by your healthcare professional and to use the injection technique recommended for this medication.

Mechanism of Action

Insulin Glargine, the active ingredient in Basugine, works by mimicking the effects of natural insulin in the body. It helps regulate glucose metabolism by promoting the uptake of glucose from the bloodstream into cells, where it can be used for energy or stored for future use. Insulin Glargine has a long duration of action, providing steady and consistent blood sugar control throughout the day.

Side Effects

Common side effects may include injection site reactions such as redness, swelling, or itching. These reactions are usually mild and temporary. Serious side effects are rare but can include allergic reactions, low blood sugar (hypoglycemia), or high blood sugar (hyperglycemia). Monitor your blood sugar levels regularly and to seek medical attention if you experience any unusual symptoms.

Drug Interactions

Basugine may interact with other medications, including oral antidiabetic drugs, certain blood pressure medications, and corticosteroids. These interactions can affect blood sugar control and may require adjustments in medication dosages. Inform your healthcare professional about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements, to avoid potential drug interactions.

Precautions

Before using Basugine, inform your healthcare professional about any medical conditions you have, especially if you have a history of allergic reactions to insulin or any other components of the medication. Certain medical conditions, such as kidney or liver disease, may require special precautions or dosage adjustments. Additionally, avoid alcohol consumption while using Basugine, as it can affect blood sugar control.

Storage

Basugine should be stored in a refrigerator between 2°C and 8°C (36°F and 46°F). Do not freeze the medication. Keep it away from direct heat, light, and moisture. Once opened, the medication should be used within the recommended timeframe as directed by your healthcare professional. Always check the expiration date before using the medication.

Patient Tips

• Follow the instructions provided by your healthcare professional for proper injection technique and dosage administration.
• Monitor your blood sugar levels regularly and report any significant changes or concerns to your healthcare professional.
• Keep a record of your blood sugar levels, medications, and any symptoms you experience to help your healthcare professional in managing your diabetes.
• Carry a form of identification or wear a medical alert bracelet to alert others that you have diabetes and are using insulin.
• Inform your healthcare professional about any other medications, including over-the-counter drugs and herbal supplements, that you are taking to avoid potential drug interactions.
• Maintain a healthy lifestyle by eating a balanced diet, engaging in regular physical activity, and managing stress levels to optimize the effectiveness of Basugine.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Type 1 diabetes – Managing insulin (NHS UK) [Accessed 6 Jun. 2024] (online) Available at:
• ABASAGLAR 100 units/mL KwikPen solution for injection in a pre-filled pen (Health Professionals SmPC) Available at:
• Insulin Glargine (Drugs.com) [Accessed 25 Jun. 2024] (online) Available at:
• insulin glargine (u-100) 100 unit/ml subcutaneous solution intermediate-, long-acting, and combination insulins (RX) [Accessed 17 Jun. 2024] (online) Available at:
• Insulin Glargine (rDNA origin) Injection [Accessed 18 Jun. 2024] (online) Available at:
• Rosenstock J, Bain SC, Gowda A, Jódar E, Liang B, Lingvay I, Nishida T, Trevisan R, Mosenzon O; ONWARDS 1 Trial Investigators. Weekly Icodec versus Daily Glargine U100 in Type 2 Diabetes without Previous Insulin. N Engl J Med. 2023 Jul 27;389(4):297-308. doi: 10.1056/NEJMoa2303208. Epub 2023 Jun 24. [Accessed 13 Jun. 2024] Available at: