Introduction
Benikite is a prescription medication that contains the active ingredient Benidipine. It is available under the brand name Benikite. This medication is primarily used to treat high blood pressure (hypertension).
Uses
Benikite is prescribed to patients with high blood pressure, also known as hypertension. It helps to lower blood pressure by relaxing and widening the blood vessels, allowing the blood to flow more easily. By reducing blood pressure, Benikite helps to decrease the risk of heart attacks, strokes, and other cardiovascular complications associated with high blood pressure.
Dosage and Administration
The dosage of Benikite may vary depending on the individual patient and their specific condition. Follow the instructions provided by your healthcare professional. Typically, the recommended starting dose for adults is 4 mg once daily, taken orally with or without food. Your doctor may adjust the dose based on your response to the medication. Do not exceed the prescribed dose without consulting your healthcare provider.
Mechanism of Action
Benidipine, the active ingredient in Benikite, belongs to a class of medications called calcium channel blockers. It works by selectively blocking the entry of calcium into the smooth muscle cells of the blood vessels. This action relaxes and widens the blood vessels, reducing the resistance to blood flow and lowering blood pressure. By inhibiting the calcium channels, Benidipine helps to prevent calcium-dependent muscle contraction, resulting in a decrease in blood pressure.
Side Effects
Common side effects may include dizziness, headache, flushing, swelling of the ankles, and increased heart rate. These side effects are generally mild and may subside as your body adjusts to the medication. However, if any of these side effects persist or worsen, contact your healthcare provider.
In rare cases, Benikite may cause more serious side effects. These can include chest pain, irregular heartbeat, shortness of breath, severe dizziness, or fainting. If you experience any of these symptoms, seek immediate medical attention.
Drug Interactions
inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. Certain medications may interact with Benikite and affect its effectiveness or increase the risk of side effects.
Some common drug interactions with Benikite include other blood pressure medications, antifungal medications, and certain antibiotics. Your healthcare provider will consider these potential interactions when prescribing Benikite and may adjust the dose or recommend alternative medications if necessary.
Precautions
Before taking Benikite, discuss your medical history and any existing health conditions with your healthcare provider. Inform them if you have liver disease, kidney disease, heart disease, or any allergies.
Benikite should not be taken by pregnant or breastfeeding women, as its safety in these populations has not been established. It is also not recommended for use in children.
Certain precautions should be taken while using Benikite. It may cause dizziness or lightheadedness, especially during the first few days of treatment. Avoid driving or operating machinery until you know how the medication affects you. Alcohol consumption should be limited while taking Benikite, as it may enhance the drowsiness effect.
Storage
Benikite should be stored at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.
Patient Tips
- Take Benikite exactly as prescribed by your healthcare provider. Do not skip doses or stop taking the medication without consulting them.
- It may take several weeks for Benikite to effectively lower your blood pressure. Continue taking it regularly, even if you feel well.
- If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- If you have any concerns or questions about Benikite, do not hesitate to reach out to your healthcare provider. They are the best resource for information and guidance regarding your specific condition and treatment.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Grapefruit and Grapefruit Juice Uses, Benefits & Dosage Herbal Database (Drugs.com) [Accessed 3 Jun. 2024] (online) Available at:
- Matsunaka K, Imai M, Sanda K, Yasunami N, Furuhashi A, Atsuta I, Wada H, Ayukawa Y. Therapeutic Effect of Benidipine on Medication-Related Osteonecrosis of the Jaw. Pharmaceuticals (Basel). 2022 Aug 18;15(8):1020. doi: 10.3390/ph15081020. [Accessed 18 Jun. 2024] Available at:
- Tomino Y. Renoprotective effects of the L-/T-type calcium channel blocker benidipine in patients with hypertension. Curr Hypertens Rev. 2013 May;9(2):108-14. doi: 10.2174/15734021113099990005. [Accessed 15 Jun. 2024] Available at:
- Palazzo A, Makulyte G, Goerhig D, Médard JJ, Gros V, Trottein F, Adnot S, Vindrieux D, Flaman JM, Bernard D. Benidipine calcium channel blocker promotes the death of cigarette smoke-induced senescent cells and improves lung emphysema. Aging (Albany NY). 2023 Dec 12;15(23):13581-13592. doi: 10.18632/aging.205259. Epub 2023 Dec 12. [Accessed 11 Jun. 2024] Available at:
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