Beninorm CH 4mg/12.5mg Tablet

Introduction

Beninorm CH is a prescription medication that contains two active ingredients: Benidipine and Chlorthalidone. It is a combination medication used to treat high blood pressure (hypertension).

Uses

Beninorm CH is prescribed to manage high blood pressure. It helps to relax the blood vessels, allowing the blood to flow more easily, and also helps to reduce the amount of water and sodium in the body, which can help lower blood pressure. By controlling high blood pressure, Beninorm CH can help reduce the risk of heart attacks, strokes, and other cardiovascular complications.

Dosage and Administration

The dosage of Beninorm CH may vary depending on individual factors such as the severity of hypertension and the patient’s response to treatment. Follow the instructions provided by your healthcare professional. Typically, the recommended starting dose is one tablet taken orally once daily. Your doctor may adjust the dose as needed to achieve the desired blood pressure control. Take the medication at the same time each day to maintain consistent blood levels.

Mechanism of Action

Beninorm CH contains two active ingredients with different mechanisms of action. Benidipine is a calcium channel blocker that works by blocking the entry of calcium into the smooth muscle cells of the blood vessels, resulting in relaxation and widening of the blood vessels. Chlorthalidone is a diuretic that works by increasing the excretion of water and sodium from the body, which helps reduce the volume of fluid in the blood vessels and lowers blood pressure. The combined action of these two ingredients helps to lower blood pressure by reducing the resistance in the blood vessels and decreasing the fluid volume.

Side Effects

be aware of these potential effects and to seek medical attention if they occur. Common side effects may include dizziness, headache, flushing, swelling in the ankles, and increased urination. These side effects are usually mild and temporary.

In some cases, Beninorm CH may cause more serious side effects. These can include irregular heartbeat, chest pain, severe dizziness, difficulty breathing, or signs of an allergic reaction such as rash, itching, or swelling. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Beninorm CH may interact with certain medications, potentially affecting their effectiveness or increasing the risk of side effects. Inform your healthcare professional about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some common drug interactions include:

• Lithium: Beninorm CH may increase the levels of lithium in the body, which can lead to lithium toxicity.
• Digoxin: Beninorm CH may increase the levels of digoxin in the body, increasing the risk of digoxin toxicity.
• Potassium-sparing diuretics: Concurrent use of Beninorm CH with potassium-sparing diuretics may increase the risk of high potassium levels in the blood.

This is not an exhaustive list of drug interactions, and other medications may also interact with Beninorm CH. Consult your healthcare professional for a complete list of potential interactions.

Precautions

Before taking Beninorm CH, inform your healthcare professional about any existing medical conditions, allergies, or medications you are currently taking. Certain precautions should be considered, including:

• Contraindications: Beninorm CH is contraindicated in patients with a known hypersensitivity to any of the ingredients or other dihydropyridine calcium channel blockers, sulfonylureas, or sulfonamide-derived drugs. It should also be avoided in patients with severe kidney or liver impairment, severe heart failure, or a history of angioedema.
• Pregnancy and breastfeeding: Beninorm CH should be used with caution during pregnancy and breastfeeding. Discuss the potential risks and benefits with your healthcare professional.
• Other medications: Beninorm CH may interact with other medications, as mentioned in the previous section on drug interactions.

Follow your healthcare professional’s instructions and to notify them of any changes in your health status or medication regimen.

Storage

Beninorm CH should be stored at room temperature, away from moisture and direct sunlight. Keep the medication out of the reach of children and pets. Do not use the medication after the expiration date printed on the packaging. If you have any unused or expired medication, consult your pharmacist or healthcare professional for proper disposal instructions.

Patient Tips

• Take the medication as prescribed: Follow your healthcare professional’s instructions regarding the dosage and administration of Beninorm CH. Do not change the dose or stop taking the medication without consulting your doctor.
• Monitor your blood pressure: Regularly check your blood pressure as directed by your healthcare professional. This will help ensure that the medication is effectively controlling your blood pressure.
• Stay hydrated: While taking Beninorm CH, drink an adequate amount of fluids to prevent dehydration.
• Avoid alcohol: Alcohol can interact with Beninorm CH and may increase the risk of side effects. It is advisable to avoid or limit alcohol consumption while taking this medication.
• Follow a healthy lifestyle: In addition to taking medication, adopting a healthy lifestyle can help manage high blood pressure. This includes maintaining a balanced diet, engaging in regular physical activity, managing stress, and avoiding smoking.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Grapefruit and Grapefruit Juice Uses, Benefits & Dosage Herbal Database (Drugs.com) [Accessed 3 Jun. 2024] (online) Available at:
• chlorthalidone (RX) [Accessed 13 Jun. 2024] (online) Available at:
• Chlorthalidone (MedlinePlus) [Accessed 14 Jun. 2024] (online) Available at:
• Matsunaka K, Imai M, Sanda K, Yasunami N, Furuhashi A, Atsuta I, Wada H, Ayukawa Y. Therapeutic Effect of Benidipine on Medication-Related Osteonecrosis of the Jaw. Pharmaceuticals (Basel). 2022 Aug 18;15(8):1020. doi: 10.3390/ph15081020. [Accessed 18 Jun. 2024] Available at: