Benperidol 30mg/20mg Capsule SR

Introduction

Benperidol is a prescription medication that contains two active ingredients: Domperidone and Omeprazole. Domperidone is a medication that helps to relieve symptoms of nausea and vomiting. Omeprazole belongs to a class of medications called proton pump inhibitors, which reduce the amount of acid produced in the stomach. Benperidol is primarily used to treat gastrointestinal conditions such as acid reflux, heartburn, and stomach ulcers.

Uses

Benperidol is prescribed for the following conditions or diseases:

• Acid reflux: It helps to reduce the symptoms of acid reflux, such as heartburn, regurgitation, and difficulty swallowing.
• Gastric and duodenal ulcers: It is used to treat and prevent ulcers in the stomach and the upper part of the small intestine.
• Gastroesophageal reflux disease (GERD): It helps to manage the symptoms of GERD, including heartburn, regurgitation, and chest pain.
• Dyspepsia: It can be used to relieve symptoms of indigestion, such as bloating, discomfort, and early satiety.

Dosage and Administration

Benperidol should be taken exactly as prescribed by your healthcare provider. The dosage and duration of treatment will depend on your specific condition and medical history. Follow the instructions provided by your healthcare provider, as they may adjust the dosage to suit your needs.

These capsules are usually taken orally, with a glass of water. It is recommended to take Benperidol before meals to enhance its effectiveness. Swallow the capsule whole without crushing or chewing it, as this may affect the release of the medication.

Mechanism of Action

The two active ingredients in Benperidol work in different ways to provide relief from gastrointestinal symptoms.

• Domperidone: It works by blocking dopamine receptors in the brain and gut, which helps to reduce nausea and vomiting. This medication also increases the movement of food through the stomach and intestines, thereby relieving symptoms of indigestion and acid reflux.
• Omeprazole: It belongs to a class of medications known as proton pump inhibitors. Omeprazole blocks the enzyme responsible for producing stomach acid, thereby reducing the amount of acid produced. This helps to relieve symptoms of acid reflux, heal and prevent ulcers, and manage symptoms of GERD.

Side Effects

Common side effects may include:

• Headache
• Dizziness
• Diarrhea
• Stomach pain
• Nausea

If any of these side effects persist or worsen, consult your healthcare provider.

In some cases, Benperidol may cause serious side effects. These can include:

• Allergic reactions: Signs of an allergic reaction may include rash, itching, swelling, severe dizziness, or difficulty breathing. Seek immediate medical attention if you experience any of these symptoms.
• Irregular heartbeat
• Severe stomach pain
• Signs of liver problems: These may include yellowing of the skin or eyes, dark urine, or persistent nausea.

If you experience any serious side effects, contact your healthcare provider immediately.

Drug Interactions

Benperidol may interact with other medications, including over-the-counter drugs and herbal supplements. Inform your healthcare provider about all the medications you are currently taking, including prescription and non-prescription drugs.

Some common drug interactions with Benperidol may include:

• Medications that reduce stomach acid (such as antacids)
• Medications that interact with the liver enzymes (such as certain antibiotics or antifungal medications)
• Medications that prolong the QT interval (such as certain antibiotics or antidepressants)
• Medications metabolized by the CYP2C19 enzyme (such as certain blood thinners or anti-seizure medications)

These are not the only possible drug interactions. Always consult your healthcare provider or pharmacist for a complete list of potential drug interactions.

Precautions

Before taking Benperidol, consider the following precautions:

• Contraindications: Benperidol should not be taken if you have a known hypersensitivity or allergy to any of its ingredients. It is also contraindicated in patients with certain medical conditions, such as liver disease or a history of cardiac arrhythmias. Consult your healthcare provider for more information.
• Interactions with other medications or substances: Benperidol may interact with certain medications, including those mentioned in the drug interactions section. Inform your healthcare provider about all the medications and substances you are currently using.

Storage

Benperidol should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not use Benperidol after the expiration date printed on the packaging.

Patient Tips

Here are some additional tips for patients using Benperidol:

• Follow the prescribed dosage and schedule provided by your healthcare provider.
• Take the medication before meals, as directed.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not double the dose to make up for a missed dose.
• If you have any questions or concerns about the medication, consult your healthcare provider or pharmacist.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Domperidone: anti-sickness medicine for nausea and vomiting (NHS UK) [Accessed 10 Jun. 2024] (online) Available at:
• Domperidone 10 mg film-coated tablets (Health Professionals SmPC) Available at:
• Domperidone (Drugs.com) [Accessed 4 Jun. 2024] (online) Available at:
• omeprazole (RX/OTC) [Accessed 7 Jun. 2024] (online) Available at:
• Definitions of Digestive Terms (International Foundation for Gastrointestinal Disorders) [Accessed 3 Jun. 2024] (online) Available at:
• Puoti MG, Assa A, Benninga M, Broekaert IJ, Carpi FJM, Deganello Saccomani M, Dolinsek J, Homan M, Mas E, Miele E, Tzivinikos C, Thomson M, Borrelli O. Drugs in Focus: Domperidone. J Pediatr Gastroenterol Nutr. 2023 Aug 1;77(2):e13-e22. doi: 10.1097/MPG.0000000000003822. Epub 2023 May 9. [Accessed 7 Jun. 2024] Available at: