Introduction
Biogram is a prescription medication that contains the active ingredient Fosfomycin. It is available under the brand name Biogram. This medication is primarily used to treat urinary tract infections (UTIs).
Uses
Biogram is prescribed for the treatment of uncomplicated urinary tract infections caused by susceptible strains of bacteria. It is commonly used to treat infections of the bladder and the lower urinary tract. UTIs can cause symptoms such as frequent urination, pain or burning during urination, and a strong urge to urinate. Biogram helps to eliminate the bacteria causing the infection and relieve these uncomfortable symptoms.
Dosage and Administration
The recommended dosage of Biogram for adults is 3 grams (1 sachet), dissolved in a glass of water, taken as a single dose. Follow the instructions provided by your healthcare professional. The medication should be taken on an empty stomach, preferably at bedtime or at least 2 to 3 hours after a meal.
Mechanism of Action
Fosfomycin, the active ingredient in Biogram, works by interfering with the synthesis of bacterial cell walls. It inhibits an enzyme called enolpyruvyl transferase, which is essential for the formation of a component called peptidoglycan in the bacterial cell wall. This disruption weakens and eventually kills the bacteria, helping to clear the infection.
Side Effects
Common side effects may include:
- Nausea
- Diarrhea
- Stomach pain
- Headache
- Dizziness
If any of these side effects persist or worsen, consult your healthcare professional. Additionally, there may be rare but serious side effects associated with the use of Biogram. These can include severe allergic reactions, such as difficulty breathing, rash, itching, or swelling. If you experience any of these serious side effects, seek immediate medical attention.
Drug Interactions
Biogram may interact with certain medications, potentially affecting their efficacy or increasing the risk of side effects. Inform your healthcare professional about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some common drug interactions include:
- Probenecid: May increase the levels of Biogram in the body, leading to an increased risk of side effects.
- Antacids containing magnesium or aluminum: May decrease the absorption of Biogram, reducing its effectiveness.
Discuss these potential interactions with your healthcare professional before starting Biogram.
Precautions
Before taking Biogram, inform your healthcare professional about any allergies, medical conditions, or medications you are currently taking. This medication may not be suitable for individuals with certain conditions or those taking specific medications. Some important precautions to consider include:
- Allergy to fosfomycin or any other ingredients in the medication
- Severe kidney impairment
- Pregnancy or breastfeeding
follow your healthcare professional’s guidance and discuss any potential risks or concerns before starting Biogram.
Storage
Patient Tips
- Take Biogram as directed by your healthcare professional.
- complete the full course of treatment, even if you start to feel better before the medication is finished.
- Drink plenty of water to stay hydrated while taking this medication.
- If you experience any unusual or severe side effects, contact your healthcare professional immediately.
- Avoid consuming alcoholic beverages while taking Biogram, as it may increase the risk of side effects.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Alexi 3g granules for oral solution (Health Professionals SmPC) Available at:
- Fosfomycin (Drugs.com) [Accessed 8 Jun. 2024] (online) Available at:
- fosfomycin tromethamine 3 gram oral packet phosphonic acid, antibacterials (RX) [Accessed 6 Jun. 2024] (online) Available at:
- Fosfomycin (MedlinePlus) [Accessed 1 Jun. 2024] (online) Available at:
- Falagas ME, Vouloumanou EK, Samonis G, Vardakas KZ. Fosfomycin. Clin Microbiol Rev. 2016 Apr;29(2):321-47. doi: 10.1128/CMR.00068-15. [Accessed 11 Jun. 2024] Available at:
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