Bisolet A 5mg/5mg Tablet

Introduction

Bisolet A is a prescription medication that contains two active ingredients: Amlodipine and Bisoprolol. Amlodipine belongs to a class of drugs called calcium channel blockers, while Bisoprolol is a beta-blocker. This combination medication is primarily used to treat high blood pressure (hypertension) in adults. It works by relaxing blood vessels and slowing down the heart rate, helping to lower blood pressure and reduce the workload on the heart.

Uses

Bisolet A is prescribed to manage high blood pressure in adults. High blood pressure can increase the risk of heart attacks, strokes, and other cardiovascular complications. By lowering blood pressure, this medication helps to reduce these risks and improve overall cardiovascular health.

Dosage and Administration

The recommended dosage of Bisolet A may vary depending on individual factors such as age, medical condition, and response to treatment. Follow your healthcare provider’s instructions carefully. Generally, the starting dose for most adults is one tablet taken once daily. Your doctor may adjust the dose as needed to achieve the desired blood pressure control. The tablets can be taken with or without food, but should be swallowed whole with a glass of water.

Mechanism of Action

Amlodipine, one of the active ingredients in Bisolet A, works by blocking calcium channels in the blood vessels, thereby preventing calcium from entering the smooth muscle cells. This leads to relaxation and dilation of the blood vessels, reducing peripheral resistance and lowering blood pressure.

Bisoprolol, the other active ingredient, is a beta-blocker that works by blocking the action of certain natural substances in the body, such as adrenaline. By doing so, it reduces the heart rate and the force of contraction of the heart muscle, which helps to lower blood pressure.

Side Effects

Common side effects may include dizziness, headache, fatigue, nausea, and flushing. These side effects are usually mild and temporary. However, if they persist or worsen, consult your healthcare provider.

Serious side effects are rare but can occur. These may include slow heart rate, low blood pressure, shortness of breath, swelling of the ankles or feet, and unusual tiredness. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Bisolet A may interact with other medications, including those available over-the-counter, herbal supplements, and vitamins. Inform your healthcare provider about all the medications you are taking to avoid potential interactions. Some common drug interactions may include:

• Other blood pressure medications: Taking Bisolet A with other medications that lower blood pressure may cause an excessive drop in blood pressure.
• Non-steroidal anti-inflammatory drugs (NSAIDs): These medications, commonly used for pain relief, may reduce the effectiveness of Bisolet A in lowering blood pressure.
• CYP3A4 inhibitors: Medications that inhibit the CYP3A4 enzyme, such as certain antifungal medications and some antibiotics, may increase the levels of Amlodipine in the body, leading to an increased risk of side effects.

Consult your healthcare provider or pharmacist for a comprehensive list of potential drug interactions.

Precautions

Before taking Bisolet A, inform your healthcare provider about any pre-existing medical conditions, allergies, or medications you are currently taking. This medication may not be suitable for everyone. Precautions and contraindications include:

• Allergy: If you have a known allergy or hypersensitivity to Amlodipine, Bisoprolol, or any other ingredients in Bisolet A, do not take this medication.
• Pregnancy and breastfeeding: Bisolet A should be used with caution during pregnancy and breastfeeding. Consult your healthcare provider for guidance.
• Heart conditions: If you have certain heart conditions, such as heart block or heart failure, special precautions may be necessary when taking this medication. Your healthcare provider will assess the risks and benefits on an individual basis.

Storage

Bisolet A should be stored at room temperature, away from excessive heat, moisture, and direct sunlight. Keep the medication out of the reach of children and pets. Do not use the tablets if they are past the expiration date printed on the packaging. If you have any unused or expired medication, dispose of it properly according to local regulations.

Patient Tips

• Take Bisolet A exactly as prescribed by your healthcare provider.
• Do not stop taking this medication without consulting your doctor, as sudden discontinuation can lead to a rebound increase in blood pressure.
• Follow a healthy lifestyle, including a balanced diet, regular exercise, and stress management, to complement the effects of the medication.
• If you miss a dose, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose and resume your regular dosing schedule.
• If you have any concerns or questions about your medication, do not hesitate to consult your healthcare provider or pharmacist for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

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• Amlodipine / Valsartan 10 mg / 160 mg film-coated tablets (Health Professionals SmPC) Available at:
• Amlodipine (Drugs.com) [Accessed 13 Jun. 2024] (online) Available at:
• amlodipine (RX) [Accessed 22 Jun. 2024] (online) Available at:
• Amlodipine (MedlinePlus) [Accessed 24 Jun. 2024] (online) Available at:
• van Zwieten PA. Amlodipine: an overview of its pharmacodynamic and pharmacokinetic properties. Clin Cardiol. 1994 Sep;17(9 Suppl 3):III3-6. [Accessed 6 Jun. 2024] Available at: