Bonitar 100 Tablet

Introduction

Bonitar is a prescription medication that contains the active ingredient Bosutinib. It is available under the brand name Bonitar. This medication is primarily used for the treatment of certain types of leukemia, specifically chronic myeloid leukemia (CML).

Uses

Bonitar is prescribed to patients who have been diagnosed with chronic myeloid leukemia (CML). It is used to treat both newly diagnosed cases of CML as well as cases that have not responded to other treatments. This medication works by inhibiting the growth of cancer cells, helping to slow down the progression of the disease.

Dosage and Administration

The dosage of Bonitar will vary depending on individual factors such as the patient’s age, weight, and overall health condition. Follow the instructions provided by your healthcare professional or the information on the prescription label. Typically, Bonitar is taken orally with a meal, once daily. Swallow the tablet whole with a glass of water, without crushing or chewing it.

Mechanism of Action

Bosutinib, the active ingredient in Bonitar, belongs to a class of medications called tyrosine kinase inhibitors. It works by blocking the activity of certain proteins, known as tyrosine kinases, that are involved in the growth and multiplication of cancer cells. By inhibiting these proteins, Bonitar helps to slow down the growth of leukemia cells, ultimately reducing the progression of the disease.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, stomach pain, fatigue, headache, and rash. Note that not all patients will experience these side effects, and they may vary in severity. If you experience any severe or persistent side effects, seek medical attention.

In rare cases, Bonitar may cause serious side effects such as bleeding problems, fluid retention, kidney problems, liver problems, and lung problems. Contact your healthcare professional immediately if you experience any signs of these serious side effects, including unusual bleeding or bruising, swelling, shortness of breath, or yellowing of the skin or eyes.

Drug Interactions

inform your healthcare professional about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. Some medications may interact with Bonitar and affect its effectiveness or increase the risk of side effects. Common drug interactions may include certain antibiotics, antifungal medications, HIV medications, and certain medications used to treat heart conditions.

Precautions

Before starting treatment with Bonitar, inform your healthcare professional about any medical conditions you have, especially liver or kidney problems. This medication may not be suitable for everyone, and discuss any potential risks or contraindications with your healthcare professional.

Bonitar may interact with certain medications, including other tyrosine kinase inhibitors and medications that affect liver function. Avoid or use caution when taking these medications together, as it may increase the risk of side effects.

Storage

Bonitar should be stored at room temperature, away from moisture and heat. Keep it in its original packaging, and away from the reach of children and pets. Do not use Bonitar if it has expired or if the packaging is damaged.

Patient Tips

• Take Bonitar exactly as prescribed by your healthcare professional. Do not change the dosage or stop taking the medication without consulting your doctor.
• It is recommended to take Bonitar with a meal to help reduce the risk of stomach upset.
• If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not crush, chew, or break the tablet. Swallow it whole with a glass of water.
• If you experience any severe or persistent side effects, contact your healthcare professional immediately.
• Inform your healthcare professional about all the medications you are currently taking, including over-the-counter and herbal products, to avoid potential drug interactions.
• Store Bonitar in a cool, dry place, away from direct sunlight, moisture, and heat.
• Follow all storage instructions provided by your healthcare professional or on the prescription label.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Bosulif 100 mg film-coated tablets (Health Professionals SmPC) Available at:
• Bosutinib (Drugs.com) [Accessed 23 Jun. 2024] (online) Available at:
• bosutinib tablet (RX) [Accessed 9 Jun. 2024] (online) Available at:
• Bosutinib (MedlinePlus) [Accessed 25 Jun. 2024] (online) Available at:
• [No authors listed] Bosutinib. 2021 Aug 16. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. [Accessed 1 Jun. 2024] Available at: