Introduction
Brestozol is a prescription medication that contains the active ingredient Anastrozole. It is available in tablet form and is used for the treatment of certain types of breast cancer in postmenopausal women.
Uses
Brestozol is primarily prescribed to treat hormone receptor-positive breast cancer, which is a type of breast cancer that relies on hormones like estrogen to grow. It is commonly used in the adjuvant (post-surgery) treatment of early-stage breast cancer, as well as for the treatment of advanced-stage breast cancer that has spread to other parts of the body.
Dosage and Administration
The dosage of Brestozol will vary depending on the specific condition being treated, the patient’s overall health, and other factors. Follow the instructions provided by your healthcare professional. Typically, the recommended dose is one tablet taken orally once a day, with or without food. Take the medication at the same time each day to maintain consistent blood levels.
Mechanism of Action
Anastrozole, the active ingredient in Brestozol, belongs to a class of medications called aromatase inhibitors. It works by reducing the production of estrogen in the body. Estrogen can promote the growth of hormone receptor-positive breast cancer cells. By inhibiting the production of estrogen, Brestozol helps to slow down or stop the growth of cancer cells.
Side Effects
Common side effects may include hot flashes, joint pain, fatigue, headache, and nausea. These side effects are generally mild and temporary. However, if they persist or become bothersome, consult your healthcare professional.
Serious side effects are rare but may include bone loss or fractures, heart problems, and allergic reactions. Seek immediate medical attention if you experience any signs of a serious allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing.
Drug Interactions
Brestozol may interact with other medications, including tamoxifen, estrogen-containing therapies, and certain antidepressants. Inform your healthcare professional about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements, to avoid potential interactions.
Precautions
Before taking Brestozol, inform your healthcare professional if you have a history of liver disease, osteoporosis, or any other medical conditions. Additionally, let your healthcare professional know if you are pregnant, planning to become pregnant, or breastfeeding, as the medication may not be suitable for these situations.
Brestozol should not be used in premenopausal women or in individuals with known hypersensitivity to Anastrozole or any of the inactive ingredients in the tablet.
Storage
Brestozol should be stored at room temperature, away from moisture and heat. Keep the medication out of the reach of children and pets. Do not use Brestozol if the packaging is damaged or if the expiration date has passed.
Patient Tips
- Take Brestozol exactly as prescribed by your healthcare professional. Do not take more or less than the recommended dose.
- If you miss a dose, take it as soon as you remember, unless it is close to the time for your next dose. In that case, skip the missed dose and resume your regular dosing schedule.
- Inform your healthcare professional about any other medications you are taking, including over-the-counter drugs and herbal supplements.
- Attend all scheduled appointments with your healthcare professional for regular check-ups and monitoring of your condition.
- If you experience any concerning side effects or have any questions or concerns, contact your healthcare professional for guidance.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Anastrozole: a medicine to treat and prevent breast cancer (NHS UK) [Accessed 17 Jun. 2024] (online) Available at:
- Anastrozole 1 mg film-coated tablets (Health Professionals SmPC) Available at:
- Anastrozole (Drugs.com) [Accessed 28 Jun. 2024] (online) Available at:
- anastrozole 1 mg tablet aromatase inhibitors (RX) [Accessed 12 Jun. 2024] (online) Available at:
- Anastrozole (MedlinePlus) [Accessed 7 Jun. 2024] (online) Available at:
- Cuzick J, Sestak I, Forbes JF, Dowsett M, Cawthorn S, Mansel RE, Loibl S, Bonanni B, Evans DG, Howell A; IBIS-II investigators. Use of anastrozole for breast cancer prevention (IBIS-II): long-term results of a randomised controlled trial. Lancet. 2020 Jan 11;395(10218):117-122. doi: 10.1016/S0140-6736(19)32955-1. Epub 2019 Dec 12. [Accessed 29 Jun. 2024] Available at:
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