Brimoeye-T Ophthalmic Solution

Introduction

Brimoeye-T is a prescription medication that combines two active ingredients: Timolol and Brimonidine. It is available in the form of eye drops and is used to treat certain eye conditions.

Uses

Brimoeye-T is primarily prescribed to lower intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. By reducing the pressure inside the eye, this medication helps to prevent further damage to the optic nerve and maintain good eye health.

Dosage and Administration

follow the dosage instructions provided by your healthcare professional. Typically, the recommended dose for Brimoeye-T is one drop in the affected eye(s) twice daily. Your doctor may adjust the dosage based on your individual needs and response to the medication. Administer the eye drops exactly as prescribed.

To use Brimoeye-T:

Wash your hands thoroughly before handling the eye drops.

Tilt your head back and look up.

Gently pull down your lower eyelid to create a small pocket.

Hold the dropper close to your eye, without touching it.

Squeeze the bottle and release one drop into the pocket formed by the lower eyelid.

Close your eyes gently for a few seconds to allow the medication to spread evenly.

If you are using the eye drops in both eyes, repeat the process for the other eye.

Mechanism of Action

Brimoeye-T contains two active ingredients: Timolol and Brimonidine. Timolol belongs to a class of medications called beta blockers, which work by reducing the production of aqueous humor, the fluid that fills the front part of the eye. By decreasing the amount of fluid produced, Timolol helps to lower intraocular pressure.

Brimonidine, on the other hand, is a selective alpha-2 adrenergic agonist. It works by reducing the production of aqueous humor and increasing the outflow of fluid from the eye, further helping to lower intraocular pressure.

Together, the combination of Timolol and Brimonidine in Brimoeye-T helps to effectively lower intraocular pressure and manage the symptoms of open-angle glaucoma and ocular hypertension.

Side Effects

Common side effects may include:

• Eye irritation or redness
• Dry eyes
• Blurred vision
• Stinging or burning sensation in the eyes
• Sensitivity to light

If any of these side effects persist or worsen, contact your healthcare professional for further guidance.

In rare cases, Brimoeye-T may cause more serious side effects. These can include:

• Allergic reactions (such as rash, itching, or swelling of the face, tongue, or throat)
• Eye pain or discomfort
• Changes in heart rate or blood pressure
• Changes in mood or mental health

If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

inform your healthcare professional about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some medications may interact with Brimoeye-T, potentially affecting its effectiveness or increasing the risk of side effects. Common drug interactions may include:

• Beta blockers or calcium channel blockers taken orally, as they may enhance the effects of Timolol.
• Monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants, as they may increase the risk of side effects related to Brimonidine.

To ensure your safety and the effectiveness of the medication, disclose your complete medication history to your healthcare professional.

Precautions

Before using Brimoeye-T, discuss any existing medical conditions or allergies with your healthcare professional. This medication may not be suitable for everyone. Precautions and contraindications may include:

• Allergy to any of the ingredients in the eye drops
• Asthma or chronic obstructive pulmonary disease (COPD)
• Heart problems or low blood pressure
• Diabetes
• Depression or other mood disorders

Additionally, inform your healthcare professional about any other eye medications you are using to avoid potential interactions.

Storage

Proper storage of Brimoeye-T is essential to maintain its effectiveness and ensure patient safety. Keep the bottle tightly closed when not in use, and store it at room temperature, away from direct sunlight and moisture. Do not freeze the medication. Keep it out of the reach of children and pets.

Patient Tips

• Follow the dosage instructions provided by your healthcare professional.
• Wash your hands before using the eye drops to prevent contamination.
• If you wear contact lenses, remove them before administering the eye drops. Wait at least 15 minutes before reinserting them.
• If you are using other eye medications, wait at least 5 minutes between each medication to prevent interactions.
• If you experience any eye discomfort or changes in vision, contact your healthcare professional.
• Attend regular eye check-ups as recommended by your doctor to monitor the effectiveness of the medication and assess any potential side effects.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Timolol tablets: medicine used to treat high blood pressure (NHS UK) [Accessed 17 Jun. 2024] (online) Available at:
• Alphagan 0.2% w/v (2 mg/ml) eye drops, solution (Health Professionals SmPC) Available at:
• Brimonidine ophthalmic (Drugs.com) [Accessed 1 Jun. 2024] (online) Available at:
• brimonidine 0.2 %-timolol 0.5 % eye drops ophthalmic antiglaucoma agents (RX) [Accessed 14 Jun. 2024] (online) Available at:
• Brimonidine Ophthalmic (MedlinePlus) [Accessed 1 Jun. 2024] (online) Available at:
• Bakheit AH, Alomar AM, Darwish H, Alkahtani HM. Brimonidine. Profiles Drug Subst Excip Relat Methodol. 2023;48:1-37. doi: 10.1016/bs.podrm.2022.11.001. Epub 2023 Feb 24. [Accessed 8 Jun. 2024] Available at: