Cabozat 20mg Tablet

Introduction

Cabozat is a prescription medication that contains the active ingredient Cabozantinib. It is available under the brand name Cabozat. This medication is primarily used to treat certain types of cancer, including advanced renal cell carcinoma (a type of kidney cancer) and hepatocellular carcinoma (a type of liver cancer). Cabozat works by inhibiting the growth of cancer cells and blocking the formation of new blood vessels in tumors.

Uses

Cabozat is prescribed to patients with advanced renal cell carcinoma and hepatocellular carcinoma who have previously received systemic therapy. It is used as a treatment option when other medications have not been effective or have stopped working. Your healthcare provider will determine if Cabozat is appropriate for your specific condition and medical history.

Dosage and Administration

follow your healthcare provider’s instructions when taking Cabozat. The dosage may vary depending on your individual needs and the specific cancer being treated. Cabozat is typically taken orally, with or without food. Swallow the tablet whole with a glass of water, and do not crush or chew it.

Mechanism of Action

Cabozat belongs to a class of medications known as kinase inhibitors. It works by inhibiting the activity of certain proteins, including receptor tyrosine kinases, which are involved in the growth and spread of cancer cells. By blocking these proteins, Cabozat helps to slow down the growth of tumors and prevent the formation of new blood vessels in cancerous tissues.

Side Effects

Common side effects include fatigue, diarrhea, nausea, loss of appetite, weight loss, and high blood pressure. These side effects are usually mild to moderate and can be managed with supportive care. However, if you experience any severe or persistent side effects, contact your healthcare provider immediately.

Serious side effects of Cabozat may include liver problems, bleeding, blood clots, heart problems, and a condition called osteonecrosis of the jaw. These side effects are rare but can be serious. If you notice any signs of liver problems (such as yellowing of the skin or eyes, dark urine, or abdominal pain), signs of bleeding (such as unusual bruising or bleeding from the gums), chest pain, shortness of breath, or jaw pain or swelling, seek medical attention right away.

Drug Interactions

Cabozat may interact with other medications, including those available over-the-counter, herbal supplements, and vitamins. Inform your healthcare provider about all the medications and supplements you are currently taking. Certain medications, such as strong CYP3A4 inhibitors and inducers, may affect how Cabozat works or increase the risk of side effects. Your healthcare provider will carefully consider any potential drug interactions before prescribing Cabozat.

Precautions

Before starting Cabozat, inform your healthcare provider about any medical conditions you have, including liver problems, bleeding disorders, heart problems, and any allergies. This medication may not be suitable for everyone, and your healthcare provider will determine if it is appropriate for you.

Avoid grapefruit and grapefruit juice while taking Cabozat, as they can increase the levels of the medication in your blood and potentially lead to an increased risk of side effects. Additionally, Cabozat may cause wound healing complications, so inform your healthcare provider about any planned surgeries or dental procedures.

Storage

Cabozat should be stored at room temperature, away from moisture and heat. Keep the medication in its original container, and make sure it is out of reach of children and pets. Do not use Cabozat if the packaging is damaged or if the expiration date has passed.

Patient Tips

• Take Cabozat exactly as prescribed by your healthcare provider. Do not change the dosage or stop taking the medication without consulting your healthcare provider first.
• If you experience diarrhea while taking Cabozat, stay hydrated by drinking plenty of fluids. Your healthcare provider may also recommend medications to manage diarrhea.
• attend all scheduled appointments with your healthcare provider for regular check-ups and monitoring while taking Cabozat.
• If you have any questions or concerns about Cabozat or its potential side effects, do not hesitate to contact your healthcare provider for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Cabometyx 20 mg Film-coated Tablets (Health Professionals SmPC) Available at:
• Cabozantinib (Drugs.com) [Accessed 26 Jun. 2024] (online) Available at:
• cabozantinib tablet (RX) [Accessed 16 Jun. 2024] (online) Available at:
• Cabozantinib (MedlinePlus) [Accessed 14 Jun. 2024] (online) Available at:
• Choueiri TK, Powles T, Burotto M, Escudier B, Bourlon MT, Zurawski B, Oyervides Juárez VM, Hsieh JJ, Basso U, Shah AY, Suárez C, Hamzaj A, Goh JC, Barrios C, Richardet M, Porta C, Kowalyszyn R, Feregrino JP, Żołnierek J, Pook D, Kessler ER, Tomita Y, Mizuno R, Bedke J, Zhang J, Maurer MA, Simsek B, Ejzykowicz F, Schwab GM, Apolo AB, Motzer RJ; CheckMate 9ER Investigators. Nivolumab plus Cabozantinib versus Sunitinib for Advanced Renal-Cell Carcinoma. N Engl J Med. 2021 Mar 4;384(9):829-841. doi: 10.1056/NEJMoa2026982. [Accessed 4 Jun. 2024] Available at: