Introduction
Calcigard is a prescription medication that contains Nifedipine as its active ingredient. It is available under the brand name Calcigard. This medication belongs to a class of drugs called calcium channel blockers. It is primarily used to treat certain cardiovascular conditions.
Uses
Calcigard is prescribed to manage certain conditions, including:
- Hypertension: It helps lower high blood pressure, reducing the risk of heart attacks, strokes, and kidney problems.
- Angina: It can be used to relieve chest pain caused by angina, a condition where the heart muscle does not receive enough oxygen-rich blood.
Dosage and Administration
- The dosage of Calcigard may vary depending on the individual’s condition and response to treatment. Follow the instructions provided by your healthcare professional.
- The capsules are usually taken orally with or without food.
- Swallow the capsules whole and do not crush or chew them unless directed by your doctor.
- take the medication at the same time(s) each day to maintain a consistent level in your body.
- Do not stop taking Calcigard without consulting your healthcare professional, as sudden discontinuation may cause your condition to worsen.
Mechanism of Action
Calcigard works by relaxing and widening the blood vessels, which helps improve blood flow and reduces the workload on the heart. This is achieved by blocking the entry of calcium into the smooth muscle cells of the blood vessels, leading to their relaxation. By reducing the resistance in the blood vessels, Calcigard helps to lower blood pressure and relieve angina symptoms.
Side Effects
Common side effects may include:
- Headache
- Flushing
- Dizziness
- Swelling in the ankles or feet
- Nausea
Contact your doctor immediately if you experience any of the following serious side effects:
- Chest pain or tightness
- Rapid heartbeat
- Fainting
- Severe dizziness
- Shortness of breath
- Allergic reactions such as rash, itching, or swelling
Drug Interactions
Calcigard may interact with other medications, including:
- CYP3A4 Inhibitors: Medications that inhibit the enzyme CYP3A4, such as certain antifungal medications, may increase the levels of Calcigard in the body, potentially leading to an increased risk of side effects.
- Beta-blockers: Combining Calcigard with beta-blockers may result in an increased risk of side effects, such as low blood pressure or heart rate.
- Grapefruit Juice: Consuming grapefruit juice while taking Calcigard may increase the levels of the medication in the body and potentially lead to an increased risk of side effects.
Inform your healthcare professional about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements, to avoid potential drug interactions.
Precautions
Before taking Calcigard, consider the following precautions:
- Allergies: Inform your doctor if you have any known allergies to nifedipine or any other medications.
- Liver or Kidney Problems: If you have any pre-existing liver or kidney conditions, your doctor may need to adjust the dosage of Calcigard.
- Pregnancy and Breastfeeding: Calcigard should be used with caution during pregnancy or breastfeeding. Consult your doctor for guidance.
- Grapefruit: Avoid consuming grapefruit or grapefruit juice while taking this medication, as it may increase the risk of side effects.
Disclose your complete medical history and provide a list of all medications you are currently taking to your healthcare professional to ensure the safe use of Calcigard.
Storage
Calcigard should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use the medication if it has expired or shows signs of deterioration. Properly discard any unused medication following the appropriate disposal guidelines.
Patient Tips
- Follow the dosage instructions provided by your healthcare professional and take the medication at the same time(s) each day for optimal results.
- Do not crush or chew the capsules unless instructed by your doctor.
- If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- Avoid consuming grapefruit or grapefruit juice while on Calcigard, as it may interact with the medication.
- If you experience any concerning side effects or have any questions or concerns, contact your healthcare professional for guidance.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Nifedipine: a medicine to treat high blood pressure (NHS UK) [Accessed 21 Jun. 2024] (online) Available at:
- Adalat LA 30 mg prolonged-release tablets (Health Professionals SmPC) Available at:
- Nifedipine (Drugs.com) [Accessed 24 Jun. 2024] (online) Available at:
- nifedipine (RX) [Accessed 2 Jun. 2024] (online) Available at:
- Nifedipine (MedlinePlus) [Accessed 15 Jun. 2024] (online) Available at:
- Raemsch KD, Sommer J. Pharmacokinetics and metabolism of nifedipine. Hypertension. 1983 Jul-Aug;5(4 Pt 2):II18-24. doi: 10.1161/01.hyp.5.4_pt_2.ii18. [Accessed 14 Jun. 2024] Available at:
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