Carezine 500mg Tablet

Introduction

Carezine is a prescription medication that contains the active ingredient Ranolazine. It is available under the brand name Carezine. This medication is primarily used to treat chronic angina, a condition characterized by chest pain or discomfort caused by reduced blood flow to the heart muscle.

Uses

Carezine is prescribed to patients with chronic angina. It helps to reduce the frequency of angina attacks and improve exercise tolerance in individuals with this condition. It is typically used in combination with other angina medications.

Dosage and Administration

The dosage of Carezine may vary depending on the individual’s specific condition and response to treatment. Follow the instructions provided by your healthcare professional. Typically, the recommended starting dose is 500 mg twice daily, with a maximum dose of 1000 mg twice daily. The tablets should be swallowed whole with water and can be taken with or without food.

Mechanism of Action

Carezine works by inhibiting the late sodium current in heart muscle cells. This helps to decrease the intracellular sodium levels, which in turn reduces calcium overload, thereby improving the efficiency of the heart’s pumping function. By optimizing the use of oxygen in the heart muscle, it helps to alleviate the symptoms of chronic angina.

Side Effects

Common side effects may include dizziness, headache, constipation, nausea, and weakness. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, consult your healthcare professional.

Serious side effects are rare but can occur. These may include an irregular heartbeat, severe dizziness, fainting, shortness of breath, or signs of an allergic reaction such as rash, itching, or swelling. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Carezine may interact with certain medications, including but not limited to, strong inhibitors or inducers of CYP3A4 enzyme. Inform your healthcare professional about all the medications you are currently taking, including over-the-counter drugs, supplements, or herbal products. They can determine if any potential drug interactions may occur and adjust your treatment accordingly.

Precautions

Before starting Carezine, inform your healthcare professional about any pre-existing medical conditions, including liver or kidney problems. This medication is not recommended for patients with certain heart conditions, such as long QT syndrome or a history of heart rhythm disorders. Avoid consuming grapefruit or grapefruit juice while taking this medication, as it may increase the risk of side effects.

Storage

Carezine should be stored at room temperature, away from moisture and heat. Keep it out of reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Take Carezine exactly as prescribed by your healthcare professional. Do not change the dosage or stop taking the medication without consulting them.
• It may take several weeks for this medication to start working effectively. Be patient and continue taking it as directed.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
• Avoid consuming alcohol while taking Carezine, as it may increase the risk of certain side effects.
• If you have any concerns or questions about your treatment, do not hesitate to reach out to your healthcare professional. They are there to support and guide you throughout your treatment journey.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Ranexa 375 mg prolonged-release Tablets (Health Professionals SmPC) Available at:
• Ranolazine (Drugs.com) [Accessed 27 Jun. 2024] (online) Available at:
• ranolazine er (RX) [Accessed 12 Jun. 2024] (online) Available at:
• Ranolazine (MedlinePlus) [Accessed 0 Jun. 2024] (online) Available at:
• Kourampi I, Katsioupa M, Oikonomou E, Tsigkou V, Marinos G, Goliopoulou A, Katsarou O, Kalogeras K, Theofilis P, Tsatsaragkou A, Siasos G, Tousoulis D, Vavuranakis M. The Role of Ranolazine in Heart Failure-Current Concepts. Am J Cardiol. 2023 Dec 15;209:92-103. doi: 10.1016/j.amjcard.2023.09.066. Epub 2023 Oct 13. [Accessed 22 Jun. 2024] Available at: