Celstemx 24mg Injection

Introduction

Celstemx is a medication that contains the active ingredient Plerixafor. It is available in the form of an injection and is used for the treatment of certain types of cancer.

Uses

Celstemx is primarily prescribed for patients with multiple myeloma or non-Hodgkin’s lymphoma. It is used in combination with other anticancer medications to help increase the number of stem cells in the blood, which can then be collected and used for a stem cell transplant.

Dosage and Administration

The dosage of Celstemx will vary depending on factors such as the patient’s weight, overall health, and the specific type of cancer being treated. It is typically administered by a healthcare professional through an injection into a vein.

Mechanism of Action

Plerixafor, the active ingredient in Celstemx, works by blocking a protein called CXCR4. This protein plays a role in the movement of certain cells, including cancer cells. By blocking CXCR4, Plerixafor helps prevent cancer cells from spreading and promotes the release of stem cells into the bloodstream.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, fatigue, and injection site reactions such as pain or redness. Report any side effects to your healthcare provider.

Serious side effects may include severe allergic reactions, difficulty breathing, chest pain, or irregular heartbeat. If you experience any of these symptoms, seek immediate medical attention.

Drug Interactions

inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Certain medications may interact with Celstemx and affect its effectiveness or increase the risk of side effects. Your healthcare provider will be able to guide you on any potential drug interactions.

Precautions

Before starting treatment with Celstemx, inform your healthcare provider about any medical conditions you have, including allergies, liver or kidney problems, or any other significant health issues. Additionally, let your healthcare provider know if you are pregnant, planning to become pregnant, or breastfeeding.

Celstemx is contraindicated in patients with a known hypersensitivity to Plerixafor or any of its components. Avoid using Celstemx if you have a known history of heart problems.

Storage

Patient Tips

• Follow the dosage instructions provided by your healthcare provider and do not change the dose without consulting them.
• Keep all your appointments for blood tests and follow-up visits with your healthcare provider.
• If you experience any side effects or have concerns about the medication, contact your healthcare provider for guidance.
• Store the medication as instructed and do not use it if it has expired or if the liquid appears discolored or cloudy.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Mozobil 20 mg/ml solution for injection (Health Professionals SmPC) Available at:
• Plerixafor (Drugs.com) [Accessed 20 Jun. 2024] (online) Available at:
• plerixafor 24 mg/1.2 ml (20 mg/ml) subcutaneous solution cxcr4 chemokine receptor antagonists (RX) [Accessed 6 Jun. 2024] (online) Available at:
• Plerixafor Injection (MedlinePlus) [Accessed 14 Jun. 2024] (online) Available at:
• Romon I, Castillo C, Cid J, Lozano M. Use of plerixafor to mobilize haematopoietic progenitor cells in healthy donors. Vox Sang. 2022 Jan;117(1):6-16. doi: 10.1111/vox.13175. Epub 2021 Jun 23. [Accessed 9 Jun. 2024] Available at: