Centri Oral Suspension

Introduction

Centri is a prescription medication that contains two active ingredients: sulfamethoxazole and trimethoprim. It is available in oral suspension form and is commonly prescribed under the brand name Centri. This medication is primarily used to treat bacterial infections.

Uses

Centri is used to treat a variety of bacterial infections, including urinary tract infections, ear infections, respiratory tract infections, and gastrointestinal infections. It is effective against certain types of bacteria, such as Escherichia coli, Klebsiella species, and Streptococcus pneumoniae.

Dosage and Administration

The dosage of Centri will vary depending on the specific condition being treated, the patient’s age, and their weight. Follow the instructions provided by your healthcare provider or the directions on the prescription label. The medication is usually taken by mouth, and it is recommended to shake the oral suspension well before each use. Complete the full course of treatment, even if symptoms improve before the medication is finished.

Mechanism of Action

Centri works by inhibiting the production of certain proteins that are essential for the growth and survival of bacteria. Sulfamethoxazole and trimethoprim work together to block different steps in the bacterial synthesis of folic acid, a necessary component for the bacteria to multiply and thrive. By interfering with these processes, Centri helps to eliminate the infection and relieve symptoms.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, and skin rash. Note that not all individuals will experience these side effects, and they are typically mild and temporary. However, if any side effects persist or worsen, consult your healthcare provider.

In rare cases, Centri may cause more serious side effects, such as allergic reactions, liver problems, or blood disorders. If you experience symptoms such as difficulty breathing, swelling of the face or throat, yellowing of the skin or eyes, or unusual bleeding or bruising, seek immediate medical attention.

Drug Interactions

Centri may interact with other medications, including certain blood thinners, medications for diabetes, and certain antidepressants. Inform your healthcare provider about all the medications you are currently taking, including over-the-counter medications, herbal supplements, and vitamins. They can help determine if any potential drug interactions may occur and adjust your treatment plan accordingly.

Precautions

Before using Centri, inform your healthcare provider about any allergies you may have, especially to sulfonamide medications. Additionally, let your healthcare provider know if you have any medical conditions, such as kidney or liver disease, asthma, or a history of blood disorders. These factors may affect the safety and effectiveness of this medication.

Centri is contraindicated in individuals with a history of severe allergic reactions to sulfamethoxazole, trimethoprim, or any other component of the medication. It should also be used with caution in pregnant or breastfeeding women, as it may pass into breast milk and affect the baby.

Storage

Centri should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not use the medication if it has passed the expiration date printed on the packaging. If you have any unused medication, consult with your healthcare provider or pharmacist on the proper disposal methods.

Patient Tips

• Take Centri exactly as prescribed by your healthcare provider, even if you start feeling better. Skipping doses or stopping the medication prematurely may allow the infection to return or worsen.
• stay well hydrated while taking Centri. Drink plenty of fluids, unless otherwise instructed by your healthcare provider.
• If you develop any new symptoms or experience any unusual side effects while taking this medication, contact your healthcare provider for further guidance.
• Finish the full course of treatment as prescribed, even if you start feeling better before the medication is finished. This will help prevent the development of antibiotic resistance.
• If you have any questions or concerns about Centri, do not hesitate to reach out to your healthcare provider or pharmacist for clarification.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Co-Trimoxazole 16 mg/ 80mg per ml for Infusion (Health Professionals SmPC) Available at:
• Sulfamethoxazole Dosage Guide + Max Dose, Adjustments (Drugs.com) [Accessed 0 Jun. 2024] (online) Available at:
• sulfamethoxazole-tmp ds tablet (RX) [Accessed 9 Jun. 2024] (online) Available at:
• Sulfamethoxazole/Trimethoprim (Bactrim or Septra) and Pregnancy (Organization of Teratology Information Specialists) – PDF [Accessed 11 Jun. 2024] (online) Available at:
• Smith LG, Sensakovic J. Trimethoprim-sulfamethoxazole. Med Clin North Am. 1982 Jan;66(1):143-56. doi: 10.1016/s0025-7125(16)31448-1. [Accessed 28 Jun. 2024] Available at: