Cerox-D Tablet SR

Introduction

Cerox-D SR is a prescription medication that combines two active ingredients: Naproxen and Domperidone. Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) that helps relieve pain, inflammation, and swelling. Domperidone is a medication that helps regulate the movement of the stomach and intestines, reducing feelings of nausea and vomiting.

Uses

Cerox-D SR is primarily prescribed for the treatment of conditions such as:

• Pain: It can be used to relieve mild to moderate pain, including headaches, dental pain, menstrual cramps, and musculoskeletal pain.
• Inflammation: It can help reduce inflammation and swelling associated with conditions like arthritis, gout, and tendonitis.
• Gastrointestinal Disorders: It can be used to alleviate symptoms such as nausea, vomiting, and bloating caused by certain gastrointestinal disorders.

Please note that Cerox-D SR should only be used under the guidance of a healthcare professional and for the specific conditions they have prescribed it for.

Dosage and Administration

The dosage of Cerox-D SR will vary depending on the individual and the condition being treated. Follow the instructions provided by your healthcare professional. Generally, the recommended dose for adults is one tablet taken once or twice daily, with or without food.

Do not exceed the recommended dose or change the dosage without consulting your healthcare professional.

Mechanism of Action

Naproxen, one of the active ingredients in Cerox-D SR, works by reducing the production of certain substances in the body that cause pain, inflammation, and swelling. It belongs to a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs).

Domperidone, the other active ingredient, works by blocking certain receptors in the brain and gut, helping to regulate the movement of the stomach and intestines. This can help reduce feelings of nausea and vomiting.

Side Effects

Common side effects may include:

• Nausea
• Headache
• Stomach upset
• Dizziness

These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, you should contact your healthcare professional.

In rare cases, Cerox-D SR may cause more serious side effects. These can include:

• Severe allergic reactions (such as rash, itching, swelling, severe dizziness, or difficulty breathing)
• Stomach bleeding (which may present as dark, tarry stools or vomiting blood)
• Signs of liver problems (such as persistent nausea, vomiting, stomach pain, yellowing of the eyes or skin, dark urine)

If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Cerox-D SR may interact with other medications, including over-the-counter drugs, herbal supplements, and vitamins. Inform your healthcare professional about all the medications you are taking to avoid potential interactions.

Common drug interactions may include:

• Anticoagulants (such as warfarin): Cerox-D SR may increase the risk of bleeding when taken with these medications.
• Selective serotonin reuptake inhibitors (SSRIs): Combining Cerox-D SR with SSRIs may increase the risk of bleeding in the stomach or intestines.
• Antacids: Taking antacids with Cerox-D SR may reduce its effectiveness.

This is not an exhaustive list of drug interactions, and there may be others. Always consult your healthcare professional before starting or stopping any medications while taking Cerox-D SR.

Precautions

Before taking Cerox-D SR, inform your healthcare professional about any allergies, medical conditions, or medications you are currently taking. It is especially important to mention if you have a history of stomach ulcers, heart problems, liver disease, kidney disease, or bleeding disorders.

Cerox-D SR should be used with caution in the following situations:

• Pregnancy and breastfeeding: discuss the risks and benefits with your healthcare professional before taking Cerox-D SR during pregnancy or while breastfeeding.
• Elderly patients: Older adults may be more susceptible to the side effects of Cerox-D SR, so caution should be exercised when prescribing this medication to this population.
• Patients with asthma: Cerox-D SR may worsen asthma symptoms in some individuals.

Storage

Cerox-D SR should be stored at room temperature, away from direct sunlight and moisture. Keep it out of the reach of children and pets. Do not use the medication if it has expired or shows signs of deterioration.

Patient Tips

Here are some additional tips to keep in mind while taking Cerox-D SR:

• Follow the prescribed dosage: Take the medication exactly as prescribed by your healthcare professional. Do not exceed the recommended dose or change the dosage without consulting them.
• Take with food: Taking Cerox-D SR with food can help reduce the risk of stomach upset.
• Avoid alcohol: Drinking alcohol while taking Cerox-D SR may increase the risk of stomach bleeding and other side effects.
• Report any side effects: If you experience any unusual or persistent side effects while taking Cerox-D SR, inform your healthcare professional promptly.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Domperidone: anti-sickness medicine for nausea and vomiting (NHS UK) [Accessed 10 Jun. 2024] (online) Available at:
• Domperidone 10 mg film-coated tablets (Health Professionals SmPC) Available at:
• Domperidone (Drugs.com) [Accessed 4 Jun. 2024] (online) Available at:
• naproxen (RX) [Accessed 14 Jun. 2024] (online) Available at:
• Definitions of Digestive Terms (International Foundation for Gastrointestinal Disorders) [Accessed 3 Jun. 2024] (online) Available at:
• Puoti MG, Assa A, Benninga M, Broekaert IJ, Carpi FJM, Deganello Saccomani M, Dolinsek J, Homan M, Mas E, Miele E, Tzivinikos C, Thomson M, Borrelli O. Drugs in Focus: Domperidone. J Pediatr Gastroenterol Nutr. 2023 Aug 1;77(2):e13-e22. doi: 10.1097/MPG.0000000000003822. Epub 2023 May 9. [Accessed 7 Jun. 2024] Available at: