Clip Injection

Introduction

Clip is a prescription medication that contains Tranexamic Acid as its active ingredient. Tranexamic Acid is commonly used for its antifibrinolytic properties, which means it helps prevent excessive bleeding by inhibiting the breakdown of blood clots. This medication is available under the brand name Clip.

Uses

Clip is primarily prescribed to manage and control bleeding in various medical conditions. It is commonly used in the treatment of heavy menstrual bleeding, nosebleeds (epistaxis), and bleeding associated with surgeries or dental procedures. Additionally, it may be used in certain bleeding disorders such as hemophilia or von Willebrand disease.

Dosage and Administration

The dosage of Clip may vary depending on the individual patient and the specific condition being treated. It is usually administered by a healthcare professional, such as a doctor or nurse, in a clinical setting. The injection is typically given intravenously (into a vein) or intramuscularly (into a muscle). The exact dosage and frequency of administration should be determined by the prescribing healthcare provider.

Mechanism of Action

Tranexamic Acid, the active ingredient in Clip, works by blocking the breakdown of blood clots in the body. It does this by inhibiting the activation of a protein called plasmin, which is responsible for breaking down fibrin, a component of blood clots. By preventing the breakdown of blood clots, Tranexamic Acid helps to stabilize and control bleeding.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, headache, dizziness, and muscle pain. These side effects are usually mild and resolve on their own. However, if you experience any persistent or severe side effects, contact your healthcare provider.

In rare cases, Clip may cause serious side effects such as allergic reactions, blood clots, or seizures. Seek immediate medical attention if you experience symptoms such as difficulty breathing, chest pain, swelling of the face or throat, sudden severe headache, or seizures.

Drug Interactions

inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. Clip may interact with certain medications, including hormonal contraceptives, blood thinners, and certain anticoagulant medications. These interactions can affect the effectiveness and safety of both Clip and the other medications. Your healthcare provider will be able to advise you on any necessary adjustments or precautions.

Precautions

Before using Clip, inform your healthcare provider about any existing medical conditions or allergies you may have. This medication may not be suitable for individuals with a history of blood clots, kidney problems, or certain types of bleeding disorders. Additionally, it may interact with certain medications or substances, such as hormonal contraceptives or alcohol. Your healthcare provider can help determine if Clip is safe and appropriate for you.

Storage

Clip should be stored in a cool, dry place, away from direct sunlight and out of the reach of children. Follow the storage instructions provided by your healthcare provider or pharmacist. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Follow the dosage instructions provided by your healthcare provider. Do not exceed the recommended dose.
• If you have any questions or concerns about your treatment with Clip, consult your healthcare provider.
• Keep a record of any side effects you experience and report them to your healthcare provider.
• Inform your healthcare provider about all the medications you are taking, including over-the-counter drugs and herbal supplements.
• If you are scheduled for any surgical or dental procedures, inform the healthcare professionals involved about your use of Clip.
• Store the medication properly and check the expiration date before use.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Tranexamic acid: medicine for heavy periods and nosebleeds (NHS UK) [Accessed 2 Jun. 2024] (online) Available at:
• Cyklokapron 100 mg/mL solution for injection/infusion (Health Professionals SmPC) Available at:
• Tranexamic acid (Drugs.com) [Accessed 6 Jun. 2024] (online) Available at:
• tranexamic acid (RX) [Accessed 13 Jun. 2024] (online) Available at:
• Tranexamic Acid (MedlinePlus) [Accessed 16 Jun. 2024] (online) Available at:
• PATCH-Trauma Investigators and the ANZICS Clinical Trials Group; Gruen RL, Mitra B, Bernard SA, McArthur CJ, Burns B, Gantner DC, Maegele M, Cameron PA, Dicker B, Forbes AB, Hurford S, Martin CA, Mazur SM, Medcalf RL, Murray LJ, Myles PS, Ng SJ, Pitt V, Rashford S, Reade MC, Swain AH, Trapani T, Young PJ. Prehospital Tranexamic Acid for Severe Trauma. N Engl J Med. 2023 Jul 13;389(2):127-136. doi: 10.1056/NEJMoa2215457. Epub 2023 Jun 14. [Accessed 26 Jun. 2024] Available at: