Clokeran 5mg Tablet

Introduction

Clokeran is a prescription medication that contains the active ingredient Chlorambucil. It is available under the brand name Clokeran. This medication is primarily used in the treatment of certain types of cancer, including chronic lymphocytic leukemia and lymphomas.

Uses

Clokeran is prescribed to patients with chronic lymphocytic leukemia and certain types of lymphomas. It works by interfering with the growth and spread of cancer cells, helping to slow down the progression of the disease and improve symptoms.

Dosage and Administration

The dosage of Clokeran will vary depending on the specific condition being treated and individual patient factors. Follow the instructions provided by your healthcare provider and to take the medication exactly as prescribed. Generally, the tablets are taken orally with a full glass of water.

Mechanism of Action

Chlorambucil, the active ingredient in Clokeran, belongs to a class of medications known as alkylating agents. It works by damaging the DNA in cancer cells, which prevents them from growing and dividing. This helps to slow down the progression of the disease and may lead to regression or remission.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, loss of appetite, and hair loss. These side effects are usually temporary and will subside as your body adjusts to the medication. Report any persistent or severe side effects to your healthcare provider.

There may also be serious side effects associated with the use of Clokeran. These can include bone marrow suppression, which may lead to a decrease in the number of blood cells, and an increased risk of infections or bleeding. Contact your healthcare provider immediately if you experience any signs of infection, such as fever, chills, or persistent sore throat.

Drug Interactions

inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some medications may interact with Clokeran, potentially affecting its effectiveness or increasing the risk of side effects. Common drug interactions may include certain immunosuppressive medications, anticoagulants, and live vaccines. Follow your healthcare provider’s guidance and avoid any potential drug interactions.

Precautions

Before starting treatment with Clokeran, discuss your medical history and any current medications with your healthcare provider. Inform them if you have any allergies, liver or kidney problems, or a history of bone marrow suppression. This medication should not be used during pregnancy or while breastfeeding, as it may harm the unborn baby or pass into breast milk.

Clokeran may also interact with certain substances, such as alcohol and tobacco. Avoid or limit the use of these substances while taking this medication, as they may increase the risk of side effects or interfere with its effectiveness.

Storage

Patient Tips

• Take Clokeran exactly as prescribed by your healthcare provider. Do not change the dosage or stop taking the medication without consulting them first.
• attend regular follow-up appointments with your healthcare provider to monitor your response to the medication and to address any concerns or side effects.
• If you experience any side effects or have questions about the medication, do not hesitate to contact your healthcare provider. They are there to support you throughout your treatment journey.
• Follow any additional instructions provided by your healthcare provider regarding diet, lifestyle modifications, or other medications that may be necessary during your treatment with Clokeran.
• Store the medication in a safe and secure place, away from the reach of children and pets. Avoid exposing the tablets to excessive moisture or heat.
• If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Chlorambucil (Drugs.com) [Accessed 9 Jun. 2024] (online) Available at:
• chlorambucil tablet (RX) [Accessed 11 Jun. 2024] (online) Available at:
• Chlorambucil (MedlinePlus) [Accessed 4 Jun. 2024] (online) Available at:
• Niemann CU, Munir T, Moreno C, Owen C, Follows GA, Benjamini O, Janssens A, Levin MD, Robak T, Simkovic M, Voloshin S, Vorobyev V, Yagci M, Ysebaert L, Qi K, Qi Q, Sinet P, Parisi L, Srinivasan S, Schuier N, Baeten K, Howes A, Caces DB, Kater AP. Fixed-duration ibrutinib-venetoclax versus chlorambucil-obinutuzumab in previously untreated chronic lymphocytic leukaemia (GLOW): 4-year follow-up from a multicentre, open-label, randomised, phase 3 trial. Lancet Oncol. 2023 Dec;24(12):1423-1433. doi: 10.1016/S1470-2045(23)00452-7. Epub 2023 Nov 6. [Accessed 30 Jun. 2024] Available at: